Evidence map›Paper›PMID 32041880›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1.

Liming Yan, Yuanbo Qi, Derek Ricketson, Lei Li, Kelly Subramanian, Jinghua Zhao, Caiting Yu, Lijie Wu, Reta Sarsam, Melissa Wong and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Molecular machineries shaping the mitochondrial inner membrane.Nature reviews. Molecular cell biology · 2025
    Review
  3. Review
  4. Review
  5. Molecular mechanisms of mitochondrial dynamics.Nature reviews. Molecular cell biology · 2025
    Review
  6. Review
  7. Article
  8. OPA1, a molecular regulator of dilated cardiomyopathy.Journal of cellular and molecular medicine · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Mitochondrial dynamics proteins as emerging drug targets.Trends in pharmacological sciences · 2023
    Review
  17. Review
  18. Insights Into Mitochondrial Dynamics in Chlamydial Infection.Frontiers in cellular and infection microbiology · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Liming YanNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yuanbo QiNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Derek RicketsonDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Lei LiSchool of Medicine, Tsinghua University, Beijing 100084, China.
Kelly SubramanianDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Jinghua ZhaoCollege of Life Sciences, Nankai University, and State Key Laboratory of Medicinal Chemical Biology, Tianjin 300071, China.
Caiting YuSchool of Medicine, Tsinghua University, Beijing 100084, China.
Lijie WuiHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Reta SarsamDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Melissa WongDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Zhiyong LouSchool of Medicine, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-2728-881X
Zihe RaoNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; raozh@mail.tsinghua.edu.cn jmnunnari@ucdavis.edu huj@ibp.ac.cn.
Jodi NunnariDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616; raozh@mail.tsinghua.edu.cn jmnunnari@ucdavis.edu huj@ibp.ac.cn.
Junjie HuNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; raozh@mail.tsinghua.edu.cn jmnunnari@ucdavis.edu huj@ibp.ac.cn.ORCID 0000-0003-4712-2243
University of California, Davis · USChinese Academy of Sciences · CNTsinghua University · CNNankai University · CNShanghaiTech University · CN

Funding

Supplement Request for High throughput Image Analysis SystemR37GM097432 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NUNNARI, JODI M. · 2015 to 2020
$2.4M
Cellular basis of mtDNA transmission.R01GM126081 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NUNNARI, JODI M. · 2017 to 2020
$1.2M
NIGMS NIH HHS R01 GM126081NIGMS NIH HHS R37 GM097432
6 · The paper itself

Abstract

The fusion of inner mitochondrial membranes requires dynamin-like GTPases, Mgm1 in yeast and OPA1 in mammals, but how they mediate membrane fusion is poorly understood. Here, we determined the crystal structure of

Indexed as

Crystallography, X-RayGTP-Binding ProteinsGuanosine DiphosphateLipid MetabolismMembrane FusionMitochondriaMitochondrial ProteinsModels, MolecularMutationProtein ConformationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsGTP-Binding ProteinsGuanosine DiphosphateMGM1 protein, S cerevisiaeMitochondrial ProteinsSaccharomyces cerevisiae Proteinsdynamininner membranemembrane fusionmitochondriastructure

Identifiers

PMID32041880
PMCPMC7049166
OpenAlexW3006567658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.