Evidence map›Paper›PMID 32041766›Full record

Observational studyThe British journal of general practice : the journal of the Royal College of General Practitioners2020

Prevalence of chronic kidney disease in the community using data from OxRen: a UK population-based cohort study.

Jennifer A Hirst, Nathan Hill, Chris A O'Callaghan, Daniel Lasserson, Richard J McManus, Emma Ogburn, José M Ordóñez Mena, Brian Shine, Clare J Taylor, Maria Dla Vazquez-Montes and 2 more

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The British journal of general practice : the journal of the Royal College of General Practitioners, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Global health inequalities of chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Jennifer A HirstNuffield Department of Primary Care Health Science; NIHR Oxford Biomedical Research Centre.
Nathan HillBristol Myers Squibb Pharmaceuticals Ltd.
Chris A O'CallaghanNuffield Department of Medicine.
Daniel LassersonUniversity of Birmingham, Birmingham.
Richard J McManusNuffield Department of Primary Care Health Science.
Emma OgburnNuffield Department of Primary Care Health Science.
José M Ordóñez MenaNuffield Department of Primary Care Health Science; NIHR Oxford Biomedical Research Centre.
Brian ShineNIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford.
Clare J TaylorNuffield Department of Primary Care Health Science; NIHR Oxford Biomedical Research Centre.
Maria Dla Vazquez-MontesNuffield Department of Primary Care Health Science, University of Oxford, Oxford.
Yaling YangNuffield Department of Primary Care Health Science; NIHR Oxford Biomedical Research Centre.
Fd Richard HobbsNuffield Department of Primary Care Health Science; NIHR Oxford Biomedical Research Centre.
Nuffield Health · GBOxford Biomedical Research · USBristol-Myers Squibb (Italy) · ITOxford BioMedica (United Kingdom) · GBUniversity of Birmingham · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is a largely asymptomatic condition of diminished renal function, which may not be detected until advanced stages without screening.

aimTo establish undiagnosed and overall CKD prevalence using a cross-sectional analysis. DESIGN AND

settingLongitudinal cohort study in UK primary care.

methodParticipants aged ≥60 years were invited to attend CKD screening visits to determine whether they had reduced renal function (estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m

resultsA total of 3207 participants were recruited and 861 attended the baseline assessment. The CKD cohort consisted of 327 people with existing CKD, 257 people with CKD diagnosed through screening (CKD prevalence of 18.2%, 95% confidence interval [CI] = 16.9 to 19.6), and 277 with borderline/transient decreased renal function. In the CKD cohort, 54.4% were female, mean standard deviation (SD) age was 74.0 (SD 6.9) years, and mean eGFR was 58.0 (SD 18.4) ml/min/1.73 m

conclusionThis study found that around 44.0% of people living with CKD are undiagnosed without screening, and prevalence of CKD stages 1-5 was 18.2% in participants aged >60 years. Follow-up will provide data on annual incidence, rate of CKD progression, determinants of rapid progression, and predictors of cardiovascular events.

Indexed as

Primary Health CareAgedAged, 80 and overCohort StudiesCreatinineCross-Sectional StudiesFemaleGlomerular Filtration RateHumansMaleMiddle AgedPrevalenceRenal Insufficiency, ChronicUnited KingdomCreatininechronic kidney diseasesglomerular filtration ratekidney failureOxRenprevalenceprimary health care

Identifiers

PMID32041766
PMCPMC7015167
OpenAlexW3005715211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.