Evidence map›Paper›PMID 32041719›Full record

ArticleAntimicrobial agents and chemotherapy2020

Scope and Predictive Genetic/Phenotypic Signatures of Bicarbonate (NaHCO

Selvi C Ersoy, Mariam Otmishi, Vanessa T Milan, Liang Li, Youngju Pak, Jose Mediavilla, Liang Chen, Barry Kreiswirth, Henry F Chambers, Richard A Proctor and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 19 citations in OpenAlex.

  1. Genomic investigation and clinical correlates of theAntimicrobial agents and chemotherapy · 2024
    Trial
  2. An Achilles' heel for methicillin-resistantAntimicrobial agents and chemotherapy · 2026
    Review
  3. Article
  4. Phenotypic and genotypic correlates of the sodium bicarbonate-responsive phenotype among methicillin-resistant Staphylococcus aureus isolates from skin and soft-tissue infections.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2025
    Article
  5. Article
  6. Review
  7. Sensitizing methicillin-resistantAntimicrobial agents and chemotherapy · 2024
    Article
  8. Measuring beta-lactam minimum inhibitory concentrations inJournal of clinical microbiology · 2024
    Review
  9. Role of the NaHCOMicrobiology spectrum · 2023
    Article
  10. Article
  11. Article
  12. The NaHCOAntimicrobial agents and chemotherapy · 2022
    Article
  13. Impacts of NaHCOAntibiotics (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Reliability ofOpen forum infectious diseases · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Selvi C ErsoyThe Lundquist Institute, Torrance, California, USA.
Mariam OtmishiCalifornia State University Dominguez Hills, Carson, California, USA.
Vanessa T MilanThe Lundquist Institute, Torrance, California, USA.
Liang LiThe Lundquist Institute, Torrance, California, USA.
Youngju PakThe Lundquist Institute, Torrance, California, USA.
Jose MediavillaMeridian Health, Nutley, New Jersey, USA.
Liang ChenMeridian Health, Nutley, New Jersey, USA.
Barry KreiswirthMeridian Health, Nutley, New Jersey, USA.
Henry F ChambersUCSF School of Medicine, San Francisco, California, USA.
Richard A ProctorUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Yan Q XiongThe Lundquist Institute, Torrance, California, USA.
Vance G FowlerDuke University Medical Center, School of Medicine, Durham, North Carolina, USA.
Arnold S BayerThe Lundquist Institute, Torrance, California, USA abayer@lundquist.org.
University of California, Los Angeles · USCalifornia State University, Dominguez Hills · USDuke Medical Center · USUniversity of Wisconsin–Madison · US

Funding

The role of purine biosynthesis and stringent response in persistent MRSA endovascular infectionsR01AI139244 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI XIONG, YAN Q. · 2019 to 2023
$2.2M
Bicarbonate-Mediated Enhancement of Beta-Lactam-MRSA Killing: Mechanisms and Clinical TranslatabilityR01AI146078 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI XIONG, YAN Q. · 2019 to 2023
$1.9M
NIAID NIH HHS R01 AI139244NIAID NIH HHS R01 AI146078
6 · The paper itself

Abstract

Addition of sodium bicarbonate (NaHCO

Indexed as

Anti-Bacterial AgentsBacteremiabeta-LactamsCefazolinHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsOxacillinPhenotypePredictive Value of TestsPrevalenceSodium BicarbonateStaphylococcal InfectionsAnti-Bacterial Agentsbeta-LactamsCefazolinOxacillinSodium Bicarbonateantimicrobial susceptibility testingbeta-lactamsmethicillin-resistant Staphylococcus aureussodium bicarbonate

Identifiers

PMID32041719
PMCPMC7179597
OpenAlexW3006581768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.