Evidence map›Paper›PMID 32041718›Full record

ArticleAntimicrobial agents and chemotherapy2020

Tissue Distribution of Doxycycline in Animal Models of Tuberculosis.

Martin Gengenbacher, Matthew D Zimmerman, Jansy P Sarathy, Firat Kaya, Han Wang, Marizel Mina, Claire Carter, Md Amir Hossen, Hongwei Su, Carolina Trujillo and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. CRISPRi-mediatedAntimicrobial agents and chemotherapy · 2026
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  4. Frontiers in microbiology · 2026
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  5. CRISPRi-mediated validation of candidatebioRxiv : the preprint server for biology · 2025
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  8. c-Myc inhibits macrophage antimycobacterial response inbioRxiv : the preprint server for biology · 2025
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  12. Impaired Tertiary Dentin Secretion after Shallow Injury inInternational journal of molecular sciences · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Martin GengenbacherCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.ORCID 0000-0002-0208-5920
Matthew D ZimmermanCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Jansy P SarathyCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Firat KayaCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Han WangCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Marizel MinaNew Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA.
Claire CarterCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Md Amir HossenCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.
Hongwei SuWeill Cornell Medical College, New York, New York, USA.
Carolina TrujilloWeill Cornell Medical College, New York, New York, USA.
Sabine EhrtWeill Cornell Medical College, New York, New York, USA.ORCID 0000-0002-7951-2310
Dirk SchnappingerWeill Cornell Medical College, New York, New York, USA.
Véronique DartoisCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA veronique.dartois@hmh-cdi.org.ORCID 0000-0001-9470-5009
Hackensack Meridian Health · USCornell University · USRutgers, The State University of New Jersey · US

Funding

A QTRAP 6500 LC-MS/MS System from SCIEX for high accuracy drug content analysisS10OD023524 · OD · RBHS-NEW JERSEY MEDICAL SCHOOL · PI DARTOIS, VERONIQUE · 2017 to 2017
$526k
NIH HHS S10 OD023524
6 · The paper itself

Abstract

Doxycycline, an FDA-approved tetracycline, is used in tuberculosis

Indexed as

Animal FeedAnimalsAnti-Bacterial AgentsBiological AvailabilityCalciumDisease Models, AnimalDoxycyclineFemaleGene SilencingLungMiceMycobacterium tuberculosisRabbitsTetracycline ResistanceTissue DistributionTransgenesAnti-Bacterial AgentsCalciumDoxycyclineanimal modelsdoxycyclinegenetic regulation in vivoTetRtissue penetrationtuberculosis

Identifiers

PMID32041718
PMCPMC7179585
OpenAlexW3006301159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.