Evidence map›Paper›PMID 32041712›Full record

ArticleAntimicrobial agents and chemotherapy2020

Efficacy of Ceftolozane-Tazobactam in Combination with Colistin against Extensively Drug-Resistant Pseudomonas aeruginosa, Including High-Risk Clones, in an

María Montero, Sandra Domene Ochoa, Carla López-Causapé, Brian VanScoy, Sonia Luque, Luisa Sorlí, Núria Campillo, Ariadna Angulo-Brunet, Eduardo Padilla, Núria Prim and 6 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Difficult-to-TreatAntibiotics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ceftolozane-tazobactam: When, how and why using it?Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

María MonteroInfectious Diseases Service, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group (IPAR), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Autònoma de Barcelona (UAB), CEXS-Universitat Pompeu Fabra, Barcelona, Spain mmontero@psmar.cat jhorcajada@psmar.cat.ORCID 0000-0001-5991-6804
Sandra Domene OchoaInfectious Diseases Service, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group (IPAR), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Autònoma de Barcelona (UAB), CEXS-Universitat Pompeu Fabra, Barcelona, Spain.
Carla López-CausapéServicio de Microbiología y Unidad de Investigación, Hospital Son Espases, IdISBa, Palma de Mallorca, Spain.
Brian VanScoyInstitute for Clinical Pharmacodynamics, Schenectady, New York, USA.
Sonia LuquePharmacy Service, Hospital del Mar, Barcelona, Spain.
Luisa SorlíInfectious Diseases Service, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group (IPAR), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Autònoma de Barcelona (UAB), CEXS-Universitat Pompeu Fabra, Barcelona, Spain.
Núria CampilloPharmacy Service, Hospital del Mar, Barcelona, Spain.
Ariadna Angulo-BrunetDepartament de Psicobiologia i de Metodologia de les Ciències de la Salut, Universitat Autònoma de Barcelona (UAB), Agència de Salut Pública de Catalunya, Generalitat de Catalunya, Barcelona, Spain.
Eduardo PadillaLaboratori de Referència de Catalunya, Barcelona, Spain.
Núria PrimLaboratori de Referència de Catalunya, Barcelona, Spain.
Virginia PomarInfectious Diseases Unit, Department of Internal Medicine, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Alba RiveraDepartment of Clinical Microbiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Santiago GrauPharmacy Service, Hospital del Mar, Barcelona, Spain.
Paul G AmbroseInstitute for Clinical Pharmacodynamics, Schenectady, New York, USA.
Antonio OliverServicio de Microbiología y Unidad de Investigación, Hospital Son Espases, IdISBa, Palma de Mallorca, Spain.ORCID 0000-0001-8571-2733
Juan P HorcajadaInfectious Diseases Service, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group (IPAR), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Universitat Autònoma de Barcelona (UAB), CEXS-Universitat Pompeu Fabra, Barcelona, Spain mmontero@psmar.cat jhorcajada@psmar.cat.
Universitat Autònoma de Barcelona · ESHospital Del Mar · ESHealth Research Institute of the Balearic Islands · ESHospital de Sant Pau · ESInstitute for Clinical Pharmacodynamics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combination therapy is an attractive therapeutic option for extensively drug-resistant (XDR)

Indexed as

Anti-Bacterial Agentsbeta-Lactam ResistanceCephalosporinsColistinDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsModels, BiologicalPseudomonas aeruginosaPseudomonas InfectionsTazobactamAnti-Bacterial Agentsceftolozane, tazobactam drug combinationCephalosporinsColistinTazobactamceftolozane-tazobactamcolistincombination therapyPseudomonas aeruginosa

Identifiers

PMID32041712
PMCPMC7179322
OpenAlexW3005070407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.