ArticleBMC research notes2020
Prevalence of 3.7 and 4.2 deletions in Sudanese patients with red cells hypochromia and microcytosis.
Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Consanguinity and willingness to perform premarital genetic screening in Sudan.European journal of human genetics : EJHG · 2025Article
- Gene Mutation Spectrum among Alpha-Thalassaemia Patients in Northeast Peninsular Malaysia.Diagnostics (Basel, Switzerland) · 2023Article
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Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlpha-thalassemia is a genetic disorder characterized by deletions of one or more α globin genes that result in deficient of α globin chains reducing haemoglobin concentration. The study aimed to screen 97 patients with microcytosis and hypochromasia for the 3.7 and 4.2 alpha thalassemia deletion mutations.
resultsOut of 97 patients screened, only 7 were carriers for the 3.7 deletion and all patients were negative for the 4.2 deletion. The 3.7 deletion was found in Foor, Hawsa and Rezagat Sudanese tribes. In the carriers of the 3.7 deletion, Red Blood Cells and Haematocrit were significantly increased. The Red Blood Cells were 7.23 ± 0.78 × 10
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