Evidence map›Paper›PMID 32041238›Full record

ArticleJournal of clinical medicine2020

Towards Understanding Therapeutic Failures in Masquelet Surgery: First Evidence that Defective Induced Membrane Properties are Associated with Clinical Failures.

Marjorie Durand, Laure Barbier, Laurent Mathieu, Thomas Poyot, Thomas Demoures, Jean-Baptiste Souraud, Alain-Charles Masquelet, Jean-Marc Collombet

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Bone wax spacers increase induced membrane thickness and promote osteogenesis more than polymethylmethacrylate spacers in the masquelet technique.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  3. Article
  4. Mechanisms of the Masquelet technique to promote bone defect repair and its influencing factors.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025
    Review
  5. Paracrine Influence of Masquelet's Induced Membrane on Marrow Derived Mesenchymal Stem Cells.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  6. Article
  7. Engineering the bone reconstruction surgery: the case of the masquelet-induced membrane technique.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
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  16. Review
  17. Article
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  19. Article
  20. The induced membrane technique in animal models: a systematic review.OTA international : the open access journal of orthopaedic trauma · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marjorie DurandFrench Military Biomedical Research Institute (IRBA), BP73, 91220 Brétigny-sur-Orge, France.
Laure BarbierFrench Military Biomedical Research Institute (IRBA), BP73, 91220 Brétigny-sur-Orge, France.
Laurent MathieuPercy Military Hospital, 101 avenue Henri Barbusse 92140 Clamart, France.
Thomas PoyotFrench Military Biomedical Research Institute (IRBA), BP73, 91220 Brétigny-sur-Orge, France.
Thomas DemouresBégin Military Hospital, 69 avenue de Paris, 94160 Saint-Mandé, France.
Jean-Baptiste SouraudBégin Military Hospital, 69 avenue de Paris, 94160 Saint-Mandé, France.
Alain-Charles MasqueletSaint-Antoine Hospital, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France.
Jean-Marc CollombetFrench Military Biomedical Research Institute (IRBA), BP73, 91220 Brétigny-sur-Orge, France.
Hôpital d'Instruction des Armées Bégin · FRHIA du Val-de-Grâce à Paris · FRSorbonne Université · FR

Funding

Direction Générale de l'Armement SAN-0217
6 · The paper itself

Abstract

The two-stage Masquelet induced-membrane technique (IMT) consists of cement spacer-driven membrane induction followed by an autologous cancellous bone implantation in this membrane to promote large bone defect repairs. For the first time, this study aims at correlating IMT failures with physiological alterations of the induced membrane (IM) in patients. For this purpose, we compared various histological, immunohistochemical and gene expression parameters obtained from IM collected in patients categorized lately as successfully (Responders;

Indexed as

bone defect repairinduced membraneMasquelet technique

Identifiers

PMID32041238
PMCPMC7073843
OpenAlexW3005231180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.