Evidence map›Paper›PMID 32041202›Full record

ArticleMolecules (Basel, Switzerland)2020

Amyloid-Beta

Beatriz Calvo-Flores Guzmán, SooHyun Kim, Bhavya Chawdhary, Katie Peppercorn, Warren P Tate, Henry J Waldvogel, Richard Lm Faull, Johanna Montgomery, Andrea Kwakowsky

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. The intracerebral injection of AβFrontiers in aging neuroscience · 2023
    Article
  7. Article
  8. Review
  9. Beta-Amyloid (AβMolecules (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Interplay Between Beta-Amyloid 1-42 (AβFrontiers in molecular neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Beatriz Calvo-Flores GuzmánCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
SooHyun KimCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Bhavya ChawdharyCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Katie PeppercornDepartment of Biochemistry, University of Otago, Dunedin 9054, New Zealand.
Warren P TateDepartment of Biochemistry, University of Otago, Dunedin 9054, New Zealand.
Henry J WaldvogelCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Richard Lm FaullCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.
Johanna MontgomeryCentre for Brain Research, Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-8714-7456
Andrea KwakowskyCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand.ORCID 0000-0002-3801-4956
University of Auckland · NZUniversity of Otago · NZ

Funding

Alzheimers New Zealand 3718869Alzheimers New Zealand Charitable Trust 502575Aotearoa Foundation, Centre for Brain Research, University of Auckland 3705579Brain Research New Zealand 3710638Freemasons New Zeland 3719321Health Research Council of New Zealand 3627373
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a complex and chronic neurodegenerative disorder that involves a progressive and severe decline in cognition and memory. During the last few decades a considerable amount of research has been done in order to better understand tau-pathology, inflammatory activity and neuronal synapse loss in AD, all of them contributing to cognitive decline. Early hippocampal network dysfunction is one of the main factors associated with cognitive decline in AD. Much has been published about amyloid-beta

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsCA1 Region, Hippocampalgamma-Aminobutyric AcidHippocampusMaleMemoryMiceMice, Inbred C57BLPyramidal CellsReceptors, GABA-ASynapsesSynaptic TransmissionAmyloid beta-Peptidesgamma-Aminobutyric AcidReceptors, GABA-Aamyloid-beta 4GABA 1GABAA receptor 2hippocampus 5tonic inhibition 3

Identifiers

PMID32041202
PMCPMC7037727
OpenAlexW3005373141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.