Evidence map›Paper›PMID 32041197›Full record

ArticleBiomolecules2020

Melittin-A Natural Peptide from Bee Venom Which Induces Apoptosis in Human Leukaemia Cells.

Michal Ceremuga, Maksymilian Stela, Edyta Janik, Leslaw Gorniak, Ewelina Synowiec, Tomasz Sliwinski, Przemyslaw Sitarek, Joanna Saluk-Bijak, Michal Bijak

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 99 citations in OpenAlex.

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  9. Synergistic interactions betweenProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
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  16. Article
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  19. Review
  20. The Anti-Leukemic Potential of Bee Venom.International journal of general medicine · 2025
    Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Michal CeremugaMilitary Institute of Armament Technology, Prymasa Stefana Wyszyńskiego 7, 05-220 Zielonka, Poland.
Maksymilian StelaCBRN Reconnaissance and Decontamination Department, Military Institute of Chemistry and Radiometry, Antoniego Chrusciela "Montera" 105, 00-910 Warsaw, Poland.
Edyta JanikBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Leslaw GorniakBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Ewelina SynowiecLaboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Tomasz SliwinskiLaboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0001-8385-7744
Przemyslaw SitarekDepartment of Biology and Pharmaceutical Botany, Medical University of Lodz, 90-151 Lodz, Poland.
Joanna Saluk-BijakDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Michal BijakBiohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0002-7838-4097
University of Łódź · PLMedical University of Lodz · PLMilitary Institute of Armament Technology · PLWojskowy Instytut Chemii i Radiometrii · PL

Funding

University of Lodz 506/1136
6 · The paper itself

Abstract

Bee venom is a very complex mixture produced and secreted by the honeybee (

Indexed as

AnimalsAntineoplastic AgentsApoptosisBeesBee VenomsCell Line, TumorCell SurvivalDNA DamageHumansK562 CellsLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukocytes, MononuclearMelittenMitochondriaPrecursor Cell Lymphoblastic Leukemia-LymphomaProtein BindingAntineoplastic AgentsBee VenomsMelittenapoptosisbee venomleukaemiamelittin

Identifiers

PMID32041197
PMCPMC7072249
OpenAlexW3005497787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.