Evidence map›Paper›PMID 32041184›Full record

ArticlePharmaceutics2020

Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (sfGRDDS) for Enhanced Oral Bioavailability of Nilotinib.

Hong-Liang Lin, Ling-Chun Chen, Wen-Ting Cheng, Wei-Jie Cheng, Hsiu-O Ho, Ming-Thau Sheu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hong-Liang LinSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Ling-Chun ChenDepartment of Biotechnology and Pharmaceutical Technology, Yuanpei University of Medical Technology, Hsinchu 30015, Taiwan.
Wen-Ting ChengSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Wei-Jie ChengSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Hsiu-O HoSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Ming-Thau SheuSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Taipei Medical University · TWKaohsiung Medical University · TWYuanpei University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regarding compliance and minimization of side effects of nilotinib therapy, there is a medical need to have a gastroretentive drug delivery system (GRDDS) to enhance the oral bioavailability that is able to administer an optimal dose in a quaque die (QD) or daily manner. In this study, the influence on a swelling and floating (

Indexed as

Gastroretentive drug delivery systemGRDDSKollidone SRNilotinibOral bioavailabilitySwelling and floating

Identifiers

PMID32041184
PMCPMC7076507
OpenAlexW3004527035

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.