Evidence map›Paper›PMID 32041140›Full record

ReviewMolecules (Basel, Switzerland)2020

Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review.

Mahshid Moballegh Nasery, Banafshe Abadi, Delaram Poormoghadam, Ali Zarrabi, Peyman Keyhanvar, Hashem Khanbabaei, Milad Ashrafizadeh, Reza Mohammadinejad, Shima Tavakol, Gautam Sethi

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

  1. Review
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  7. Pharmacological Insights and Technological Innovations inPharmaceuticals (Basel, Switzerland) · 2026
    Review
  8. Review
  9. Article
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  11. Article
  12. Article
  13. Review
  14. Article
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  17. Article
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mahshid Moballegh NaseryStudent Research Committee, Kerman University of Medical Sciences, Kerman 7619813159, Iran.
Banafshe AbadiStudent Research Committee, Kerman University of Medical Sciences, Kerman 7619813159, Iran.
Delaram PoormoghadamDepartment of Medical Nanotechnology, Faculty of Advanced Sciences & Technology, Pharmaceutical Sciences Branch, Islamic Azad University, (IAUPS), Tehran 1916893813, Iran.
Ali ZarrabiSabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla 34956, Istanbul, Turkey.
Peyman KeyhanvarResearch Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 5165665811, Iran.
Hashem KhanbabaeiMedical Physics Department, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran.
Milad AshrafizadehDepartment of Basic Science, Faculty of Veterinary Medicine, University of Tabriz, Tabriz 5166616471, Iran.
Reza MohammadinejadNeuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman 7616911319, Iran.
Shima TavakolCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran 1449614525, Iran.
Gautam SethiDepartment of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Todays, nano-pharmaceutics is emerging as an important field of science to develop and improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the prevention and treatment of various chronic diseases such as cancers, a number of them have displayed issues associated with their solubility, bioavailability, and bio-degradability. In the present review, we focus on curcumin, an important and widely used polyphenol, with diverse pharmacological activities such as anti-inflammatory, anti-carcinogenic, anti-viral, etc. Notwithstanding, it also exhibits poor solubility and bioavailability that may compromise its clinical application to a great extent. Therefore, the manipulation and encapsulation of curcumin into a nanocarrier formulation can overcome these major drawbacks and potentially may lead to a far superior therapeutic efficacy. Among different types of nanocarriers, biological and biopolymer carriers have attracted a significant attention due to their pleiotropic features. Thus, in the present review, the potential protective and therapeutic applications of curcumin, as well as different types of bio-nanocarriers, which can be used to deliver curcumin effectively to the different target sites will be discussed.

Indexed as

AnimalsCurcuminDrug CarriersDrug Delivery SystemsHumansNanoparticlesPolyphenolsCurcuminDrug CarriersPolyphenolsbiopolymercancercurcuminexosomes.nanocarriers

Identifiers

PMID32041140
PMCPMC7037405

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.