Evidence map›Paper›PMID 32041109›Full record

ArticleInternational journal of molecular sciences2020

Local and Systemic Humoral Response to Autologous Lineage-Negative Cells Intrathecal Administration in ALS Patients.

Bartłomiej Baumert, Anna Sobuś, Monika Gołąb-Janowska, Zofia Ulańczyk, Edyta Paczkowska, Karolina Łuczkowska, Alicja Zawiślak, Sławomir Milczarek, Bogumiła Osękowska, Agnieszka Meller and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Bartłomiej BaumertDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-9933-5844
Anna SobuśDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Monika Gołąb-JanowskaDepartment of Neurology, Pomeranian Medical University, 71-252 Szczecin, Poland.
Zofia UlańczykDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0003-0451-8723
Edyta PaczkowskaDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-7052-9741
Karolina ŁuczkowskaDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0003-4008-7473
Alicja ZawiślakDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0003-2036-2853
Sławomir MilczarekDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Bogumiła OsękowskaDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Agnieszka MellerDepartment of Neurology, Pomeranian Medical University, 71-252 Szczecin, Poland.
Karolina Machowska-SempruchDepartment of Neurology, Pomeranian Medical University, 71-252 Szczecin, Poland.
Agnieszka WełnickaDepartment of Neurology, Pomeranian Medical University, 71-252 Szczecin, Poland.
Krzysztof SafranowDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-9415-2758
Przemysław NowackiDepartment of Neurology, Pomeranian Medical University, 71-252 Szczecin, Poland.
Bogusław MachalińskiDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Pomeranian Medical University · PL

Funding

National Centre for Research and Development, Poland STRATEGMED1/234261/2NCBR/2014
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) remains a fatal disease with limited therapeutic options. Signaling via neurotrophins (NTs), neuroinflammation, and certain micro-RNAs are believed to play essential role in ALS pathogenesis. Lineage-negative stem/progenitor cells (Lin

Indexed as

Amyotrophic Lateral SclerosisBrain-Derived Neurotrophic FactorCell LineageC-Reactive ProteinFemaleGene Expression ProfilingGene Expression RegulationHumansImmunity, HumoralInjections, SpinalMicroRNAsMiddle AgedOligonucleotide Array Sequence AnalysisStem Cell TransplantationBDNF protein, humanBrain-Derived Neurotrophic FactorC-Reactive ProteinMicroRNAsMIRN16 microRNA, humanMIRN206 microRNA, humanamyotrophic lateral sclerosis (ALS)gene microarraysinflammatory responselineage-negative cellsneurotrophins

Identifiers

PMID32041109
PMCPMC7037134
OpenAlexW3005420437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.