Evidence map›Paper›PMID 32040798›Full record

ArticleJournal of autism and developmental disorders2020

Pain Modulation Mechanisms in ASD Adults.

A Dubois, M Boudjarane, A Le Fur-Bonnabesse, A Dion, G L'heveder, B Quinio, M Walter, S Marchand, C Bodéré

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. How the Brain Interprets Pain in Autistic People: Does Sex Matter?European journal of pain (London, England) · 2026
    Article
  2. A Reliable Effect of Alexithymia, but Not Autism, on Placebo Hypoalgesia.Autism : the international journal of research and practice · 2026
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A DuboisLP3C - EA1285, Department of Psychology, University of Western Brittany, Brest, France. amandine.dubois@univ-brest.fr.ORCID http://orcid.org/0000-0001-7363-1418
M BoudjaraneLIEN - EA4685, University of Western Brittany, Brest, France.
A Le Fur-BonnabesseLIEN - EA4685, University of Western Brittany, Brest, France.
A DionINSERM CIC 1412, Brest University Hospital, Brest, France.
G L'hevederNeurological Functional Explorations, Brest University Hospital, Brest, France.
B QuinioPain Center, Brest University Hospital, Brest, France.
M WalterLIEN - EA4685, University of Western Brittany, Brest, France.
S MarchandDepartment of Surgery, Faculty of Medicine, University of Sherbrooke, Sherbrooke, Canada.
C BodéréLIEN - EA4685, University of Western Brittany, Brest, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We tested endogenous pain modulation mechanisms in adults with autism spectrum disorders (ASD). Nineteen ASD adults without intellectual disabilities were included, matched with 19 healthy volunteers on the basis of sex and chronological age. An experimental pain model was used to measure excitatory and inhibitory pain mechanisms in a single session. Statistical analyses indicated that endogenous pain modulation mechanisms in ASD group did not differ significantly from those of healthy adults. The pain scores were very disparate in ASD group with a greater range of extreme scores than in control group. Unlike schizophrenic patients, there was no systematic dysfunction of endogenous excitatory pain modulation mechanisms, but the high variability requires to be wise to interpret the results and formulate conclusion.

Indexed as

AdultAutism Spectrum DisorderFemaleHumansMaleMiddle AgedPainAutismCPMExperimental painPain modulationTemporal summation

Identifiers

PMID32040798

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.