Evidence map›Paper›PMID 32040338›Full record

ReviewAnnual review of clinical psychology2020

Stress Allostasis in Substance Use Disorders: Promise, Progress, and Emerging Priorities in Clinical Research.

Gaylen E Fronk, Sarah J Sant'Ana, Jesse T Kaye, John J Curtin

Open access · greenAbstract readReview
In one paragraph

Review in Annual review of clinical psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Stressor-elicited smoking and craving during a smoking cessation attempt.Journal of psychopathology and clinical science · 2022
    Trial
  4. Exploring the nature and relationship of tobacco cigarette craving and withdrawal.Journal of psychopathology and clinical science · 2026
    Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
  11. The phenotype of recovery XI: associations of sleep quality and perceived stress with discounting and quality of life in substance use recovery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  12. Observational
  13. Article
  14. Article
  15. A Person-Centered Analysis of Craving in Smoking-Cue-Exposure Research.Clinical psychological science : a journal of the Association for Psychological Science · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gaylen E FronkDepartment of Psychology, University of Wisconsin, Madison, Wisconsin 53706, USA; email: gfronk@wisc.edu, skittleson@wisc.edu, jjcurtin@wisc.edu.
Sarah J Sant'AnaDepartment of Psychology, University of Wisconsin, Madison, Wisconsin 53706, USA; email: gfronk@wisc.edu, skittleson@wisc.edu, jjcurtin@wisc.edu.
Jesse T KayeWilliam S. Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA; email: jtkaye@wisc.edu.
John J CurtinDepartment of Psychology, University of Wisconsin, Madison, Wisconsin 53706, USA; email: gfronk@wisc.edu, skittleson@wisc.edu, jjcurtin@wisc.edu.
University of Wisconsin–Madison · US

Funding

RCT targeting noradrenergic stress mechanisms in alcoholism with doxazosinR01AA024388 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI CURTIN, JOHN J. · 2015 to 2019
$2.1M
Dynamic, real-time prediction of alcohol use lapse using mHealth technologiesR01AA024391 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI CURTIN, JOHN J. · 2015 to 2019
$1.9M
NIAAA NIH HHS R01 AA024388NIAAA NIH HHS R01 AA024391
6 · The paper itself

Abstract

Clinicians and researchers alike have long believed that stressors play a pivotal etiologic role in risk, maintenance, and/or relapse of alcohol and other substance use disorders (SUDs). Numerous seminal and contemporary theories on SUD etiology posit that stressors may motivate drug use and that individuals who use drugs chronically may display altered responses to stressors. We use foundational basic stress biology research as a lens through which to evaluate critically the available evidence to support these key stress-SUD theses in humans. Additionally, we examine the field's success to date in targeting stressors and stress allostasis in treatments for SUDs. We conclude with our recommendations for how best to advance our understanding of the relationship between stressors and drug use, and we discuss clinical implications for treatment development.

Indexed as

AllostasisBiomedical ResearchStress, PsychologicalSubstance-Related DisordersHumansaddictionallostasisstresssubstance use disorderstreatment

Identifiers

PMID32040338
PMCPMC7259491
OpenAlexW3005595706

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.