ReviewDiagnostic pathology2020
Primary pulmonary myxoid sarcoma with EWSR1-CREB1 fusion: a case report and review of the literature.
Review in Diagnostic pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Tumor-type-specific expression of TTF-1 in primary central nervous system tumors classified by the 2021 WHO criteria.The journal of pathology. Clinical research · 2026Article
- Primary pulmonary myxoid sarcoma with detectedAME case reports · 2026Article
- Primary pulmonary myxoid sarcoma: A case report.Oncology letters · 2025Article
- A case report of myxoma within the right submandibular muscle and a literature review.Frontiers in surgery · 2025Article
- Primary mucinous sarcoma of the lung with EWSR1 translocation: a case report.Frontiers in medicine · 2025Article
- Primary Pulmonary Myxoid Sarcoma Located in the Left Lung Parenchyma: Case Report with a Review of Literature.Surgical case reports · 2025Article
- Review
- Clinical and pathological analyses of 14 cases of angiomatoid fibrous histiocytoma.Medical molecular morphology · 2024Article
- Primary pulmonary myxoid sarcoma in the interlobar fissure of the left lung lobe: a case report.BMC pulmonary medicine · 2024Article
- Primary pulmonary myxoid sarcoma with EWSR1::CREB1 fusion: a literature review.Journal of cancer research and clinical oncology · 2024Review
- Neobaicalein prevents isoflurane anesthesia-induced cognitive impairment in neonatal mice via regulating CREB1.Clinics (Sao Paulo, Brazil) · 2023Article
- CT findings of a large primary pulmonary myxoid sarcoma: A case report.Radiology case reports · 2022Article
- Comprehensive genomic profiling of EWSR1/FUS::CREB translocation-associated tumors uncovers prognostically significant recurrent genetic alterations and methylation-transcriptional correlates.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022Article
- Distinct clinicopathological features of pulmonary primary angiomatoid fibrous histiocytoma: A report of four new cases and review of the literature.Thoracic cancer · 2021Review
- Primary pulmonary myxoid sarcoma: report of one case and literature review.International journal of clinical and experimental pathology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary pulmonary myxoid sarcoma (PPMS) is an extremely rare lung sarcoma that is characterized in most cases by recurrent balanced chromosomal translocation t(2;22)(q33;q12) leading to the oncogenic fusion gene EWSR1-CREB1. CASE PRESENTATION: We report a case of PPMS with molecular confirmation using fluorescence in situ hybridization (FISH) and DNA sequencing in a 45-year-old female patient. Computer tomography (CT) scanning revealed a peripheral circumscribed solid mass of 2.1 × 2 cm in the right lung superior lobe. Histologically, the tumor cells ranged from stellate, polygonal to chondrocyte-like or physaliferous-like, forming reticular network of delicate lace-like cellular strands and cords in abundant myxoid stroma. The tumor cell immunophenotype was positive for vimentin, EMA and negative for CK-pan, TTF-1, CAM5.2, S-100, calponin, SMA, desmin, ALK, CD31 and CD34. Molecular analysis demonstrated EWSR1-CREB1 gene fusion in this tumor. During 38 months of follow-up, the patient was alive with no clinical or radiological evidence of recurrence or metastasis.
conclusionPPMS is a rare low-grade sarcoma with distinct histological and genetic features. We add another case to the literature of this rare tumor and report for the first time occurrence of chondrocyte-like and physaliferous-like tumor cells in this tumor, thus enriching its morphologic and cytologic spectrum.
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