Evidence map›Paper›PMID 32039370›Full record

ArticleJHEP reports : innovation in hepatology2019

Quantitative digital pathology reveals association of cell-specific

Bynvant Sandhu, Maria C Perez Matos, Stephanie Tran, Alexander Zhong, Eva Csizmadia, Misung Kim, Mark A Herman, Imad Nasser, Michelle Lai, Z Gordon Jiang

Open access · goldAbstract read
In one paragraph

Article in JHEP reports : innovation in hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. [Analytical value of histological research and application of RNAscope technology in liver diseases].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020
    Review
  6. The current issue of JHEP Reports.JHEP reports : innovation in hepatology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Bynvant SandhuDivision of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Maria C Perez MatosDivision of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Stephanie TranDivision of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Alexander ZhongDivision of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Eva CsizmadiaDivision of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Misung KimDivision of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Mark A HermanDivision of Endocrinology, Duke University Medical Center, Durham, NC.
Imad NasserDepartment of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Medical School, Boston, MA.
Michelle LaiDivision of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Z Gordon JiangDivision of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Harvard University · USBeth Israel Deaconess Medical Center · USDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimsThe I148M variant (rs738409) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) is by far the most important genetic determinant of non-alcoholic fatty liver disease (NAFLD). However, in the context of NAFLD, the transcriptional regulation of

methodsThe abundance of

resultsWhile the majority of

conclusionsLAY SUMMARY: A genetic variant in patatin-like phospholipase domain-containing protein 3 (or

Indexed as

COL1αcollagen 1αliver fibrosisNASHNon-alcoholic fatty liver diseasenon-alcoholic steatohepatitispatatin-like phospholipase domain-containing protein 3RNAscope

Identifiers

PMID32039370
PMCPMC7001539
OpenAlexW2956014653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.