Evidence map›Paper›PMID 32039211›Full record

ArticleFrontiers in cell and developmental biology2020

Dose-Dependent Effects of GLD-2 and GLD-1 on Germline Differentiation and Dedifferentiation in the Absence of PUF-8.

Youngyong Park, Samuel O'Rourke, Faten A Taki, Mohammad A Alfhili, Myon Hee Lee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Biology · 2024
    Review
  3. ADR-2 regulates fertility and oocyte fate inbioRxiv : the preprint server for biology · 2024
    Article
  4. Article
  5. Article
  6. Molding immortality from a plastic germline.Current opinion in cell biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Youngyong ParkDepartment of Internal Medicine, Division of Hematology/Oncology, Brody School of Medicine at East Carolina University, Greenville, NC, United States.
Samuel O'RourkeDepartment of Internal Medicine, Division of Hematology/Oncology, Brody School of Medicine at East Carolina University, Greenville, NC, United States.
Faten A TakiDepartment of Pharmacology, Weill Cornell Medical College, New York, NY, United States.
Mohammad A AlfhiliDepartment of Internal Medicine, Division of Hematology/Oncology, Brody School of Medicine at East Carolina University, Greenville, NC, United States.
Myon Hee LeeDepartment of Internal Medicine, Division of Hematology/Oncology, Brody School of Medicine at East Carolina University, Greenville, NC, United States.
East Carolina University · USCornell University · USKing Saud University · SA

Funding

Action Mechanisms of Resveratrol in Somatic Longevity and Reproductive SystemR15AG060373 · NIA · EAST CAROLINA UNIVERSITY · PI LEE, MYON HEE · 2018 to 2019
$459k
Role of PUF-8/Pumilio in GLP-1/Notch-Mediated Germline Proliferation in C. elegansR15GM112174 · NIGMS · EAST CAROLINA UNIVERSITY · PI LEE, MYON HEE · 2015 to 2015
$367k
NIA NIH HHS R15 AG060373NIGMS NIH HHS R15 GM112174
6 · The paper itself

Abstract

PUMILIO/FBF (PUF) proteins have a conserved function in stem cell regulation.

Indexed as

C. elegansdedifferentiationdifferentiationGLD-2PUF-8

Identifiers

PMID32039211
PMCPMC6992537
OpenAlexW3002861302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.