ArticleJournal of International Society of Preventive & Community Dentistry
Evaluate Efficacy of Desensitizing Toothpaste Containing Zinc-carbonate Hydroxyapatite Nanocrystals: Non-comparative Eight-week Clinical Study.
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- The Decision Tree for Clinical Management of Dentin Hypersensitivity. A Consensus Report.Oral health & preventive dentistry · 2022Pooled it
- Clinical Status and Salivary aMMP-8 Evaluation of 0.12% Chlorhexidine Versus MicroRepairDentistry journal · 2026Article
- Occlusion of Dentinal Tubules by Nanohydroxyapatite and Zinc Carbonate Hydroxyapatite-Based Toothpastes as Desensitizing Agents: An in Vitro Study.Frontiers in dentistry · 2025Article
- Dental Applications of Ion-Substituted Hydroxyapatite: A Review of the Literature.Dentistry journal · 2024Review
- The Effect of Oral Care Foams and a Spray on Salivary pH Changes after Exposure to Acidic Beverages in Young Adults.Dentistry journal · 2024Article
- Improving Oral Health with Fluoride-Free Calcium-Phosphate-Based Biomimetic Toothpastes: An Update of the Clinical Evidence.Biomimetics (Basel, Switzerland) · 2023Review
- Remineralization of Dentinal Lesions Using Biomimetic Agents: A Systematic Review and Meta-Analysis.Biomimetics (Basel, Switzerland) · 2023Review
- Biomimetic Action of Zinc Hydroxyapatite on Remineralization of Enamel and Dentin: A Review.Biomimetics (Basel, Switzerland) · 2023Review
- Clinical Evidence of Biomimetic Hydroxyapatite in Oral Care Products for Reducing Dentin Hypersensitivity: An Updated Systematic Review and Meta-Analysis.Biomimetics (Basel, Switzerland) · 2023Review
- Hydroxyapatite in Oral Care Products-A Review.Materials (Basel, Switzerland) · 2021Review
- Evaluation of remineralizing effect of zinc-carbonate hydroxyapatite on the reduction of postrestorative sensitivity: A randomized controlled clinical trial.Journal of conservative dentistry : JCDArticle
- The Effect of Toothpastes Containing Hydroxyapatite, Fluoroapatite, and Zn-Mg-hydroxyapatite Nanocrystals on Dentin Hypersensitivity: A Randomized Clinical Trial.Journal of International Society of Preventive & Community DentistryArticle
- Qualitative and Quantitative Assessment of Remineralizing Effect of Prophylactic Toothpaste Promoting Brushite Formation: A Randomized Clinical Trial.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study was to evaluate the clinical effectiveness of desensitizing toothpaste in reducing the dentine hypersensitivity (DH). MATERIALS AND
methodsThe study was a before and after clinical trial conducted to evaluate the clinical efficacy of a desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals (Zn-CHA) for controlling DH. The trial involved 72 patients with DH who were evaluated four and eight weeks after using Zn-CHA toothpaste. The sensitivity was assessed by airblast method using Schiff Sensitivity Scale.
resultsRepeated measures analysis of variance test was used to compare baseline score with fourth and eighth week. Statistically significant differences were observed between sensitivity scores at baseline and those at four- and eight-week intervals (
conclusionThe results suggested that the use of Zn-CHA nanocrystals dentifrice might become an effective therapy to reduce DH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.