ArticleCureus2020
Evaluation of Change in Microhardness by Application of MI Varnish on Primary Tooth Enamel, Affected by Use of Frequently Prescribed Paediatric Syrups: An In Vitro Study.
Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Assessment of Remineralization Treatment on Primary Enamel's Microhardness and Mineral Composition Post Iron Drop Interaction.International journal of dentistry · 2026Article
- Erosive Potential of Pediatric Syrup Medications on the Human Enamel: Ex Vivo Study.Dentistry journal · 2025Article
- Evaluate enamel surface staining due to iron supplements on primary teeth - AnBioinformation · 2025Article
- Effect of cheese and casein phosphopeptide-amorphous calcium phosphate on erosive lesions of primary teeth enamel following exposure to amoxicillin and ibuprofen syrups: AnDental research journal · 2024Article
- Effect of Zamzam Water on Microhardness of Primary Tooth Enamel After Erosion Induced by Claritin Syrup: AnJournal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Dental erosion is considered as an irreversible progressive loss of tooth structure due to chemical dissolution by acids not of bacterial origin. Frequent intake of syrups can be an effective factor in tooth erosion when prescribed for illnesses. In the acidic environment, MI Varnish releases calcium, phosphate and fluoride from the covering layer and the teeth can be prevented from such acidic attacks from the erosive content of the syrups. Aim To evaluate change in microhardness by application of MI Varnish on primary tooth enamel, affected by use of frequently prescribed paediatric syrups. Method The effects of three paediatric syrups (Ibugesic Plus, Novamox, Becozinc H) and distilled water (control group) with different ingredients on primary tooth enamel were evaluated. Immersion cycles were applied three times a day for one minute. The measurements of the samples prepared were taken on 0 (baseline), third, fifthand seventh day. Microhardness was measured using a Vickers hardness tester. Then, those samples were coated with MI Varnish, and changes in microhardness were evaluated using the Vickers hardness tester after one week (14th day). The pH, titratable acidity and buffer capacity of the syrups were also evaluated. Results There was a significant decrease in microhardness in all the syrups (p < 0.001) on days 3, 5, 7 and 14. Novamox syrup and distilled water (control group) were the least erosive on the primary tooth enamel and Becozinc H syrup being the most erosive on primary tooth enamel was seen. MI Varnish remineralized the enamel but not with any significant difference. Conclusion In our findings, Novamox syrup showed the least erosion on primary tooth enamel compare to other syrups. Enamel microhardness was significantly reduced on all days after immersion in all syrups. Application of MI Varnish to enamel resisted erosion but was not significant. Paedodontists should be aware of the erosive potential of all the frequently prescribed syrups and stress on compliance with oral hygiene measures and application of varnishes releasing fluoride, calcium and phosphate on the tooth.
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