Evidence map›Paper›PMID 32038792›Full record

ArticleToxicological research2008

Activation Mechanism of Protein Kinase B by DNA-dependent Protein Kinase Involved in the DNA Repair System.

Yuwen Li, Longzhen Piao, Keum-Jin Yang, Sanghee Shin, Eulsoon Shin, Kyung Ah Park, Hee Sun Byun, Minho Won, Byung Lyul Choi, Hyunji Lee and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Toxicological research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Yuwen Li *13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Longzhen Piao *13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Keum-Jin Yang13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Sanghee Shin13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Eulsoon Shin13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Kyung Ah Park13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Hee Sun Byun13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Minho Won13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Byung Lyul Choi13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Hyunji Lee13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Young-Rae Kim13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Jang Hee Hong13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Gang Min Hur13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Jeong-Lan Kim23Department of Psychiatry, College of Medicine, Chungnam National University, Taejeon, 301-131 Korea.
Jae Youl Cho33School of Bioscience and Biotechnology, and Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, 200-701 Korea.
Jeong Ho Seok13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Jongsun Park13Department of Pharmacology, Cell Signaling Laboratory, Research Center for Transgenic Cloned Pigs, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Korea.
Korea Institute of Radiological and Medical Sciences · KRChungnam National University · KRResearch Institute for Bioscience and Biotechnology · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA-dependent protein kinase (DNA-PK) is involved in joining DNA double-strand breaks induced by ionizing radiation or V(D)J recombination and is activated by DNA ends and composed of a DNA binding subunit, Ku, and a catalytic subunit, DNA-PKcs. It has been suggested that DNA-PK might be 2

Indexed as

Cell SignalingDNA damageDNA-PKInsulin signalingProtein kinase B

Identifiers

PMID32038792
PMCPMC7006269
OpenAlexW2034490539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.