Evidence map›Paper›PMID 32038655›Full record

ArticleFrontiers in immunology2020

A Single Step

Pramod Jagtap, Puja Prasad, Abhishek Pateria, Sachin D Deshmukh, Shalini Gupta

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Forsythiasides: A review of the pharmacological effects.Frontiers in cardiovascular medicine · 2022
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Pramod JagtapDepartment of Chemical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
Puja PrasadDepartment of Chemical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
Abhishek PateriaDepartment of Chemical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
Sachin D DeshmukhCenter for Sepsis Control and Care, Jena University Hospital, Jena, Germany.
Shalini GuptaDepartment of Chemical Engineering, Indian Institute of Technology Delhi, New Delhi, India.
Indian Institute of Technology Delhi · INJena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute systemic Gram-negative bacterial infections are accompanied by release of lipopolysaccharide (LPS) endotoxins into the bloodstream and an innate immune host response via the well-known toll like receptor 4 (TLR4) pathway. In this, LPS associates non-covalently with TLR4 to form an activated heterodimer (LPS/MD2/TLR4)

Indexed as

Biological AssayBlotting, WesternDynamic Light ScatteringEndotoxinsHumansImmunity, InnateIn Vitro TechniquesKineticsLigandsLipopolysaccharide ReceptorsLipopolysaccharidesLymphocyte Antigen 96Protein BindingRecombinant ProteinsSignal TransductionSilver StainingCD14 protein, humanEndotoxinsLigandsLipopolysaccharide ReceptorsLipopolysaccharidesLY96 protein, humanLymphocyte Antigen 96Recombinant ProteinsTLR4 protein, humanToll-Like Receptor 4CD14in vitro bioassayligand screeningLPSMD2TLR4

Identifiers

PMID32038655
PMCPMC6992608
OpenAlexW3002247895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.