Evidence map›Paper›PMID 32038598›Full record

ArticleFrontiers in microbiology2020

Stimulated Biosynthesis of an C10-Deoxy Heptaene NPP B2

Heung-Soon Park, Hye-Jin Kim, Chi-Young Han, Hee-Ju Nah, Si-Sun Choi, Eung-Soo Kim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Journal of microbiology and biotechnology · 2022
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heung-Soon ParkDepartment of Biological Engineering, Inha University, Incheon, South Korea.
Hye-Jin KimDepartment of Biological Engineering, Inha University, Incheon, South Korea.
Chi-Young HanDepartment of Biological Engineering, Inha University, Incheon, South Korea.
Hee-Ju NahDepartment of Biological Engineering, Inha University, Incheon, South Korea.
Si-Sun ChoiDepartment of Biological Engineering, Inha University, Incheon, South Korea.
Eung-Soo KimDepartment of Biological Engineering, Inha University, Incheon, South Korea.
Inha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyene macrolides, such as nystatin A1, amphotericin B, and NPP A1, belong to a large family of valuable antifungal polyketide compounds that are typically produced by soil actinomycetes. Previously, NPP B1, a novel NPP A1 derivative harboring a heptaene core structure, was generated by introducing two amino acid substitutions in the putative NADPH-binding motif of the enoyl reductase domain in module 5 of the NPP A1 polyketide synthase in

Indexed as

antifungal activityhemolytic toxicitypolyenePseudonocardia autotrophicaregulatory genes

Identifiers

PMID32038598
PMCPMC6993583
OpenAlexW3002582447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.