ArticleFrontiers in physiology2019
Geometry of the Carotid Artery and Its Association With Pathologic Changes in a Chinese Population.
Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06756724 (Morphometric Insights Into Stroke Development), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Morphometric Insights Into Stroke Development: Analyzing Bifurcation Angles and Diameters of Common and Internal Carotid Arteries Using Frankfurt Plane Reoriented Images
Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Comparative assessment of corneal biomechanical parameters in lactating versus non-lactating women: implications for refractive surgery candidates.International ophthalmology · 2026Article
- Age-related geometric analysis of the extracranial artery for endovascular access planning.Quantitative imaging in medicine and surgery · 2026Article
- Article
- Associations between electrocardiogram and carotid ultrasound parameters: a healthy chinese group study.Frontiers in physiology · 2022Article
- Yes-Associated Protein in Atherosclerosis and Related Complications: A Potential Therapeutic Target That Requires Further Exploration.Frontiers in cardiovascular medicine · 2021Review
- Gut microbiota in atherosclerosis: focus on trimethylamine N-oxide.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCarotid artery geometry influences blood flow disturbances and is thus an important risk factor for carotid atherosclerosis. Extracellular matrix (ECM) and yes-associated protein (YAP) expression may play essential roles in the pathophysiology of carotid artery stenosis, but the effect of blood flow disturbances of carotid bifurcation location on the ECM is unknown. We hypothesized that carotid artery anatomy and geometry are independently associated with the ECM and YAP expression.
methodsIn this cross-sectional study, 193 patients were divided into two groups: an asymptomatic group (
resultsSymptomatic patients had increased carotid bifurcation angle and laminar shear stress compared to asymptomatic patients (
conclusionGeometry of the carotid artery and position relative to cervical spine might be associated with ECM and YAP protein expression, which could contribute to carotid artery stenosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.