ReviewFrontiers in aging neuroscience2019
Functional Near-Infrared Spectroscopy to Study Cerebral Hemodynamics in Older Adults During Cognitive and Motor Tasks: A Review.
Review in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 54 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Different Attentional Focus During Walking on Prefrontal Cortical Activation in Young Healthy Adults
Effects of Different Attentional Focus During Walking on Prefrontal Cortical Activation in Older Adults and Patients With Parkinson's Disease
Effects of Blood Pressure on Cognition and Cerebral Blood Flow in Parkinson Disease
Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of functional near-infrared spectroscopy-based task paradigms in stroke rehabilitation.Frontiers in human neuroscience · 2025Pooled it
- Brain activation of the PFC during dual-task walking in stroke patients: A systematic review and meta-analysis of functional near-infrared spectroscopy studies.Frontiers in neuroscience · 2023Pooled it
- Prefrontal cortex activation while walking did not change but gait speed improved after a randomized physical therapy intervention.Aging clinical and experimental research · 2024Trial
- Exercise interventions, postural control, and prefrontal cortex activation in older adults.Brain and cognition · 2023Trial
- Neural Substrates for Hand and Shoulder Movement in Healthy Adults: A Functional near Infrared Spectroscopy Study.Brain topography · 2023Trial
- Effects of different dual task training on dual task walking and responding brain activation in older adults with mild cognitive impairment.Scientific reports · 2022Trial
- Orthostatic hypotension and acute cognitive dysfunction in Parkinson's disease: insights from functional near-infrared spectroscopy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Article
- Alpha-Band EEG Modulation as a Potential Aged-Related Biomarker for Biofeedback-Driven Motor-Cognitive Adaptability.Sensors (Basel, Switzerland) · 2026Article
- Prefrontal Cortical Asymmetry and Motor Slowing in Older Women: EEG Evidence That Fear of Falling Modulates Emotional Valence and Reaction Time.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Article
- Locomotor savings relies on attentional control of walking in older, but not younger adults.bioRxiv : the preprint server for biology · 2026Article
- Digital instrument simulator platform to support the development of noninvasive optical NIR device for placenta monitoring.Journal of biomedical optics · 2026Article
- Multidimensional assessment of cognitive function in community-dwelling older adults: fNIRS dual-task assessment and nutritional evaluation in Japanese salons.Frontiers in public health · 2026Article
- Biophilic Design and Restorative Effects: A Neuropsychological Study of Healthy Indoor Workspaces in Urban Contexts.International journal of environmental research and public health · 2025Article
- Nigrostriatal dopaminergic integrity in relation to prefrontal cortex activity and gait performance during dual-task walking in older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Effects of the combined letter fluency task on frontal cortex regional and dynamic oxygenation patterns.Scientific reports · 2025Article
- Brain Activation During Motor Preparation and Execution in Patients with Mild Cognitive Impairment: An fNIRS Study.Brain sciences · 2025Article
- Application of Near-Infrared Spectroscopy in Early Detection of Antidepressant Treatment Efficacy in Major Depressive Disorder: A Longitudinal Study.Actas espanolas de psiquiatria · 2025Article
- Evaluation of Neural, Systemic and Extracerebral Activations During Active Walking Tasks in Older Adults Using fNIRS.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025Article
- Quantification of Motor Learning in Hand Adjustability Movements: An Evaluation Variable for Discriminant Cognitive Decline.IEEE journal of translational engineering in health and medicine · 2025Article
- Functional connectivity and characteristics of cortical brain networks of elderly individuals under different motor cognitive tasks based on functional near-infrared spectroscopy.Frontiers in human neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
The integrity of the frontal areas of the brain, specifically the prefrontal cortex, are critical to preserve cognition and mobility in late life. Prefrontal cortex regions are involved in executive functions and gait control and have been related to the performance of dual-tasks. Dual-task performance assessment may help identify older adults at risk of negative health outcomes. As an alternative to neuroimaging techniques that do not allow assessment during actual motion, functional Near-Infrared Spectroscopy (fNIRS) is a non-invasive technique that can assess neural activation through the measurement of cortical oxygenated and deoxygenated hemoglobin levels, while the person is performing a motor task in a natural environment as well as during cognitive tasks. The aim of this review was to describe the use of fNIRS to study frontal lobe hemodynamics during cognitive, motor and dual-tasks in older adults. From the 46 included publications, 20 studies used only cognitive tasks, three studies used motor tasks and 23 used dual-tasks. Our findings suggest that fNIRS detects changes in frontal activation in older adults (cognitively healthy and mild cognitive impairment), especially while performing cognitive and dual-tasks. In both the comparison between older and younger adults, and in people with different neurological conditions, compared to healthier controls, the prefrontal cortex seems to experience a higher activation, which could be interpreted in the context of proposed neural inefficiency and limited capacity models. Further research is needed to establish standardized fNIRS protocols, study the cerebral hemodynamic in different neurological and systemic conditions that might influence cortical activation and explore its role in predicting incident health outcomes such as dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.