ReviewFrontiers in neuroinformatics2019
Animal Functional Magnetic Resonance Imaging: Trends and Path Toward Standardization.
Review in Frontiers in neuroinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 3 syntheses or guidelines pooled it, 115 citations in OpenAlex.
- Integrating Neuroimaging and Machine Learning to Predict Mental Disorder Outcomes: A Systematic Review.Advances in experimental medicine and biology · 2026Pooled it
- Where do we stand on fMRI in awake mice?Cerebral cortex (New York, N.Y. : 1991) · 2024Pooled it
- A systematic review of the relationship between magnetic resonance imaging based resting-state and structural networks in the rodent brain.Frontiers in neuroscience · 2023Pooled it
- SORDINO: silent, sensitive, specific and artifact-resistant fMRI in awake, behaving mice.Nature neuroscience · 2026Article
- Electroencephalography-functional magnetic resonance imaging using a familial temporal lobe epilepsy model in cats: an exploratory methodological pilot study.Journal of veterinary internal medicine · 2026Article
- Go figure: transparency in neuroscience images preserves context and clarifies interpretation.Nature methods · 2026Review
- Dynamic Functional Connectivity Changes in Cortical and Cortico-Striatal Strokes in Mice.CNS neuroscience & therapeutics · 2026Article
- Integration of resting-state and stimulus-fMRI uncovers reduced network flexibility in post-surgical pain.Scientific reports · 2026Article
- Longitudinal Awake Mouse fMRI During Voluntary Locomotion Using Zero TE Imaging and a Novel Treadmill Training Protocol.Magnetic resonance in medicine · 2026Article
- Measurement of electrochemical brain activity with fast-scan cyclic voltammetry during functional magnetic resonance imaging.Nature protocols · 2026Review
- Acute cannabidiol (CBD), tetrahydrocannabinol (THC) and their mixture (THC:CBD) exert differential effects on brain activity and blood flow in rats: A translational neuroimaging study.Journal of psychopharmacology (Oxford, England) · 2026Article
- Biphasic acclimation for simultaneous wide-field fluorescent CaImaging neuroscience (Cambridge, Mass.) · 2026Article
- A brain-state-informed framework for simultaneous extinction of fear and functional magnetic resonance imaging acquisition in rodents.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice.bioRxiv : the preprint server for biology · 2025Article
- Magnetic resonance imaging cerebral blood perfusion measurement in awake mice.Journal of neuroscience methods · 2025Article
- Resting-state fMRI reveals altered functional connectivity associated with resilience and susceptibility to chronic social defeat stress in mouse brain.Molecular psychiatry · 2025Article
- Aging-dependent loss of functional connectivity in a mouse model of Alzheimer's disease and reversal by mGluR5 modulator.Molecular psychiatry · 2025Article
- A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- An Overview of Anesthetic Procedures for Ferret (Mustela putorius furo) Preclinical Brain MRI: A Call for Standardization.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Review
- Glymphatic system dysfunction in cerebral infarction: advances and perspectives based on DTI-derived ALPS measures.American journal of translational research · 2025Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 12 institutions in 8 countries.
Funding
Abstract
Animal whole-brain functional magnetic resonance imaging (fMRI) provides a non-invasive window into brain activity. A collection of associated methods aims to replicate observations made in humans and to identify the mechanisms underlying the distributed neuronal activity in the healthy and disordered brain. Animal fMRI studies have developed rapidly over the past years, fueled by the development of resting-state fMRI connectivity and genetically encoded neuromodulatory tools. Yet, comparisons between sites remain hampered by lack of standardization. Recently, we highlighted that mouse resting-state functional connectivity converges across centers, although large discrepancies in sensitivity and specificity remained. Here, we explore past and present trends within the animal fMRI community and highlight critical aspects in study design, data acquisition, and post-processing operations, that may affect the results and influence the comparability between studies. We also suggest practices aimed to promote the adoption of standards within the community and improve between-lab reproducibility. The implementation of standardized animal neuroimaging protocols will facilitate animal population imaging efforts as well as meta-analysis and replication studies, the gold standards in evidence-based science.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.