Evidence map›Paper›PMID 32038114›Full record

ArticleEXCLI journal2020

5,6,7,4'-Tetramethoxyflavanone protects against neuronal degeneration induced by dexamethasone by attenuating amyloidogenesis in mice.

Kanet Pakdeepak, Ratchanaporn Chokchaisiri, Jiraporn Tocharus, Pranglada Jearjaroen, Chainarong Tocharus, Apichart Suksamrarn

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EXCLI journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kanet PakdeepakDepartment of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Ratchanaporn ChokchaisiriDepartment of Chemistry, School of Science, University of Phayao, Phayao, Thailand.
Jiraporn TocharusDepartment of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Pranglada JearjaroenGraduate School, Chiang Mai University, Chiang Mai 50200, Thailand.
Chainarong TocharusDepartment of Anatomy, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Apichart SuksamrarnDepartment of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.
Chiang Mai University · THRamkhamhaeng University · THUniversity of Phayao · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term exposure to high glucocorticoid levels induces memory impairment and neurodegeneration in Alzheimer's disease (AD) by increasing the expression of amyloid β and tau hyperphosphorylation (pTau). Previous studies showed beneficial effects of flavonoids in neurodegenerative models. 5,6,7,4'-tetramethoxyflavanone (TMF) is one of the active ingredients in

Indexed as

5,6,7,4'-tetramethoxyflavanonAlzheimer's diseaseamyloidogenesisdexamethasoneneurodegeneration

Identifiers

PMID32038114
PMCPMC7003641
OpenAlexW3008225126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.