Evidence map›Paper›PMID 32038081›Full record

ArticleJournal of human reproductive sciences

Does Double Dose of Recombinant Human Chorionic Gonadotropin for Final Follicular Maturation in

Neeta Singh, Bhavana Girish, Neena Malhotra, Reeta Mahey, Vanamail Perumal

Open access · diamondAbstract read
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The Trigger in IVF Cycles: Molecular Pathways and Clinical Implications.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Neeta SinghDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Bhavana GirishDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Neena MalhotraDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Reeta MaheyDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Vanamail PerumalDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextIn

aimsThe aim of our study was to assess the effect on the number of mature oocytes retrieved after triggering ovulation in IVF cycles using 250 μg or 500 μg of r-hCG. SETTINGS AND

designProspective, single-center, randomized study. SUBJECTS AND

methods100 women undergoing IVF with embryo transfer. The primary outcome measure was the total number of oocytes retrieved per follicle, number of mature oocytes, and number of embryos generated. The secondary outcomes included clinical and biochemical pregnancy rates and incidence of ovarian hyperstimulation syndrome.

resultsMean number of oocytes retrieved (6.5 ± 4.0 vs. 6.4 ± 3.9,

conclusionsDouble dose of r-hCG for final follicular maturation in IVF cycles resulted in improvement in mean number of oocytes per follicle but did not result in improved pregnancy rates in the women. In the subset of poor responders, 500 μg r-hCG seems to be more advantageous than the lower dose, although larger randomized trials are needed to generalize this strategy.

Indexed as

In vitro fertilizationin vitro fertilization outcomesmature oocytespoor responderrecombinant-human chorionic gonadotropin trigger

Identifiers

PMID32038081
PMCPMC6937770
OpenAlexW2995837402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.