Evidence map›Paper›PMID 32037895›Full record

ArticleDrug delivery2020

Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from

Bing Chen, Xuewen Wang, Yanyan Zhang, Kangping Huang, Hao Liu, Dafen Xu, Shaoguang Li, Qicai Liu, Jianyong Huang, Hong Yao and 1 more

Abstract readComparative Study
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Chemopreventive mechanisms of amentoflavone: recent trends and advancements.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Review
  15. Advances in the Anti-Tumor Activity of Biflavonoids inInternational journal of molecular sciences · 2023
    Review
  16. Article
  17. Review
  18. Current Trends on Solid Dispersions: Past, Present, and Future.Advances in pharmacological and pharmaceutical sciences · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bing ChenNano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.
Xuewen WangHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Yanyan ZhangHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Kangping HuangHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Hao LiuHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Dafen XuHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Shaoguang LiHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Qicai LiuNano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.
Jianyong HuangDepartment of Pharmaceutical, Fujian Medical University Union Hospital, Fuzhou, China.
Hong YaoHigher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Xinhua LinNano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amentoflavone, robustaflavone, 2″,3″-dihydro-3',3‴-biapigenin, 3',3‴-binaringenin, and delicaflavone are five major hydrophobic components in the total biflavonoids extract from

Indexed as

Administration, OralAnimalsArea Under CurveBiflavonoidsBiological AvailabilityDrug LiberationHydrophobic and Hydrophilic InteractionsMaleMiceMice, Inbred BALB CMice, NudePlant ExtractsPolymersPovidoneRatsRats, Sprague-DawleyBiflavonoidsPlant ExtractsPolymersPovidoneamorphous solid dispersionsbiflavonoidsoral bioavailabilitypolyvinylpyrrolidone K-30Selaginella doederleinii

Identifiers

PMID32037895
PMCPMC7034131

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.