ArticleThe Journal of organic chemistry2020
Water-Soluble NIR Absorbing and Emitting Indolizine Cyanine and Indolizine Squaraine Dyes for Biological Imaging.
Article in The Journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Water-Soluble Squaraine-Based NIR Chromofluorogenic Probe for HClO/ClOChemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Unveiling the Structural Modifications of Cyanines to Target G‑Quadruplex DNA through Biophysical, Computational, and Transcriptome Analyses.ACS omega · 2026Article
- A New Class of Anionic Near-Infrared Fluorescent Dyes with 1,6-Diheterophenalene-2,5-dione End Groups.Chemical & biomedical imaging · 2026Article
- Squaraine-Peptide Conjugates as Efficient Reporters of Neutrophil Extracellular Traps-Mediated Chronic Inflammation.ACS applied materials & interfaces · 2025Article
- β,β-Difluoro Peroxides as Fluorinated C2-Building Blocks for the Construction of Functionalized Indolizines.Molecules (Basel, Switzerland) · 2024Article
- Water-Soluble Small Organic Fluorophores for Oncological Theragnostic Applications: Progress and Development.Topics in current chemistry (Cham) · 2024Review
- Switch-on near infrared emission in albumin behind dark fabric: toward application in forensic latent bloodstain detection.RSC advances · 2024Article
- Latent bloodstain detection using a selective turn-on NIR fluorescence dye responsive to serum albumin.RSC advances · 2023Article
- Squaraine nanoparticles for optoacoustic imaging-guided synergistic cancer phototherapy.Nanophotonics (Berlin, Germany) · 2023Article
- Selective Near-Infrared Blood Detection Driven by Ionic Liquid-Dye-Albumin Nanointeractions.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Enantio- and diastereodivergent synthesis of fused indolizines enabled by synergistic Cu/Ir catalysis.Chemical science · 2023Article
- Photothermal bleaching of nickel dithiolene for bright multi-colored 3D printed parts.Nature communications · 2023Article
- Acid-Triggered Switchable Near-Infrared/Shortwave Infrared Absorption and Emission of Indolizine-BODIPY Dyes.Molecules (Basel, Switzerland) · 2023Article
- SWIR emissive RosIndolizine dyes with nanoencapsulation in water soluble dendrimers.RSC advances · 2021Article
- Access to 6-hydroxy indolizines and related imidazo[1,5-RSC advances · 2021Article
- Driving high quantum yield NIR emission through proquinoidal linkage motifs in conjugated supermolecular arrays.Chemical science · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Organic dyes that absorb and emit in the near-infrared (NIR) region are potentially noninvasive, high-resolution, and rapid biological imaging materials. Indolizine donor-based cyanine and squaraine dyes with water-solubilizing sulfonate groups were targeted in this study due to strong absorptions and emissions in the NIR region. As previously observed for nonwater-soluble derivatives, the indolizine group with water-solubilizing groups retains a substantial shift toward longer wavelengths for both absorption and emission with squaraines and cyanines relative to classically researched indoline donor analogues. Very high quantum yields (as much as 58%) have been observed with absorption and emission >700 nm in fetal bovine serum. Photostability studies, cell culture cytotoxicity, and cell uptake specificity profiles were all studied for these dyes, demonstrating exceptional biological imaging suitability.
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