ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2020
Clinical Utility of Preoperative Bilingual Language fMRI Mapping in Patients with Brain Tumors.
Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Standardization of presurgical language fMRI in Greek population: Mapping of six critical regions.Brain and behavior · 2022Article
- Intraoperative Brain Mapping in Multilingual Patients: What Do We Know and Where Are We Going?Brain sciences · 2022Review
- Organizing Variables Affecting fMRI Estimates of Language Dominance in Patients with Brain Tumors.Brain sciences · 2021Review
- Functional MRI study of language organization in left-handed and right-handed trilingual subjects.Scientific reports · 2020Article
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12 authors.
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Abstract
background and purposePrevious literature has demonstrated disparity in the postoperative recovery of first and second language function of bilingual neurosurgical patients. However, it is unclear to whether preoperative brain mapping of both languages is needed. In this study, we aimed to evaluate the clinical utility of language task functional MRI (fMRI) implemented in both languages in bilingual patients.
methodsWe retrospectively examined fMRI data of 13 bilingual brain tumor patients (age: 23 to 59 years) who performed antonym generation task-based fMRIs in English and non-English language. The usefulness of bilingual language mapping was evaluated using a structured survey administered to 5 neurosurgeons. Additionally, quantitative comparison between the brain activation maps of both languages was performed.
resultsSurvey responses revealed differences in raters' surgical approach, including asleep versus awake surgery and extent of resection, after viewing the language fMRI maps. Additional non-English fMRI led to changes in surgical decision-making and bettered localization of language areas. Quantitative analysis revealed an increase in laterality index (LI) in non-English fMRI compared to English fMRI. The Dice coefficient demonstrated fair overlap (.458 ± .160) between the activation maps.
conclusionBilingual fMRI mapping of bilingual patients allows to better appreciate functionally active language areas that may be neglected in single language mapping. Utility of bilingual mapping was supported by changes in both surgical approach and LI measurements, suggesting its benefit on preoperative language mapping.
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