Evidence map›Paper›PMID 32037100›Full record

Observational studyJournal of dermatological science2020

Associating filaggrin copy number variation and atopic dermatitis in African-Americans: Challenges and opportunities.

David J Margolis, Nandita Mitra, Ron Berna, Ole Hoffstad, Brian S Kim, Albert Yan, Andrea L Zaenglein, Zelma Chiesa Fuxench, Ashley M Quiggle, Cristina de Guzman Strong and 2 more

Open access · greenAbstract readLetterObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of dermatological science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Using a Machine Learning Approach to Identify Low-Frequency and RareJID innovations : skin science from molecules to population health · 2021
    Article
  4. Cracking the Skin Barrier: Liquid-Liquid Phase Separation Shines under the Skin.JID innovations : skin science from molecules to population health · 2021
    Review
  5. FLG Variation Differs between European Americans and African Americans.The Journal of investigative dermatology · 2021
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

David J MargolisDepartment of Biostatistics, Epidemiology and Informatics, Perlman School of Medicine, Philadelphia, PA, United States; Department of Dermatology, Perlman School of Medicine, Philadelphia, PA, United States; Department of Medicine, Division of Translational Medicine and Human Genetics, Perlman School of Medicine, Philadelphia, PA, United States. Electronic address: margo@pennmedicine.upenn.edu.
Nandita MitraDepartment of Biostatistics, Epidemiology and Informatics, Perlman School of Medicine, Philadelphia, PA, United States.
Ron BernaDepartment of Dermatology, Perlman School of Medicine, Philadelphia, PA, United States; Department of Medicine, Division of Translational Medicine and Human Genetics, Perlman School of Medicine, Philadelphia, PA, United States.
Ole HoffstadDepartment of Biostatistics, Epidemiology and Informatics, Perlman School of Medicine, Philadelphia, PA, United States.
Brian S KimDivision of Dermatology, Department of Medicine, Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO, United States.
Albert YanChildren's Hospital of Philadelphia, Philadelphia, PA, United States.
Andrea L ZaengleinDepartments of Dermatology and Pediatrics, Pennsylvania State University/Hershey Medical Center, PA, United States.
Zelma Chiesa FuxenchDepartment of Dermatology, Perlman School of Medicine, Philadelphia, PA, United States; Department of Medicine, Division of Translational Medicine and Human Genetics, Perlman School of Medicine, Philadelphia, PA, United States.
Ashley M QuiggleDivision of Dermatology, Department of Medicine, Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO, United States; Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States.
Cristina de Guzman StrongDivision of Dermatology, Department of Medicine, Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO, United States; Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States.
Xuan Fei Colin Cornelius WongSkin Research Institute of Singapore, A⁎STAR, Singapore.
John E CommonSkin Research Institute of Singapore, A⁎STAR, Singapore.
National Skin Centre · SGUniversity of Pennsylvania · USWashington University in St. Louis · USChildren's Hospital of Philadelphia · USPenn State Milton S. Hershey Medical Center · USTranslational Therapeutics (United States) · US

Funding

Atopic Dermatitis and High Resolution HLAR01AR070873 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MARGOLIS, DAVID, MONOS, DIMITRI S · 2017 to 2022
$2.4M
African-Americans with Atopic Dermatitis: Skin Barrier and ImmuneR01AR069062 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MARGOLIS, DAVID · 2016 to 2021
$2.4M
NOS1AP and Capon Associated Impaired Healing in Those with Diabetic Foot UlcersR01DK116199 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MARGOLIS, DAVID, THOM, STEPHEN RAYMOND · 2018 to 2021
$2.3M
Filaggrin Mutations and the Prognosis of Atopic DermatitisR01AR056755 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MARGOLIS, DAVID · 2009 to 2013
$2.0M
NIAMS NIH HHS R01 AR056755NIAMS NIH HHS R01 AR069062NIAMS NIH HHS R01 AR070873NIDDK NIH HHS R01 DK116199
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Copy Number VariationsAdolescentAdultBlack or African AmericanCase-Control StudiesChildDermatitis, AtopicFemaleFilaggrin ProteinsGenetic Predisposition to DiseaseHumansMaleMiddle AgedPolymorphism, Single NucleotideRisk FactorsS100 ProteinsFilaggrin ProteinsFLG protein, humanS100 Proteins

Identifiers

PMID32037100
PMCPMC8778950
OpenAlexW3004402263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.