Evidence map›Paper›PMID 32036739›Full record

ArticleGut microbes2020

Can gut microbiota of men who have sex with men influence HIV transmission?

Sara L Coleman, C Preston Neff, Sam X Li, Abigail J S Armstrong, Jennifer M Schneider, Sharon Sen, Blair Fennimore, Thomas B Campbell, Catherine A Lozupone, Brent E Palmer

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sara L ColemanDivision of Allergy and Clinical Immunology, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
C Preston NeffDivision of Allergy and Clinical Immunology, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
Sam X LiDivision of Allergy and Clinical Immunology, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
Abigail J S ArmstrongDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.ORCID 0000-0002-7677-8092
Jennifer M SchneiderDivision of Allergy and Clinical Immunology, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
Sharon SenDivision of Allergy and Clinical Immunology, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
Blair FennimoreDivision of Gastroenterology, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
Thomas B CampbellDivision of Infectious Diseases, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
Catherine A LozuponeDivision of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
Brent E PalmerDivision of Allergy and Clinical Immunology, Department of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado, USA.
University of Colorado Anschutz Medical Campus · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
Diet/gut Microbiome Interaction Influence Inflammatory Disease in HIV PatientsR01DK108366 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CAMPBELL, THOMAS B., LOZUPONE, CATHERINE · 2015 to 2019
$3.0M
Factors mediating gut microbiota dysbiosis and metabolic disease in HIV patientsR01DK104047 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI LOZUPONE, CATHERINE, PALMER, BRENT E · 2014 to 2018
$2.1M
HIV-associated gut microbiome affects lung immunity and pneumococcal immune responseR01HL138639 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI CAMPBELL, THOMAS B., LOZUPONE, CATHERINE · 2017 to 2020
$1.9M
NCATS NIH HHS UL1 TR000005NHLBI NIH HHS R01 HL138639NIDDK NIH HHS R01 DK104047NIDDK NIH HHS R01 DK108366
6 · The paper itself

Abstract

Gaining a complete understanding of transmission risk factors will assist in efforts to reduce new HIV infections, especially within the disproportionally affected population of men who have sex with men (MSM). We recently reported that the fecal microbiota of MSM elevates immune activation in gnotobiotic mice and enhances HIV infection

Indexed as

Gastrointestinal MicrobiomeSexual and Gender MinoritiesAdolescentAdultAntigens, CDBiopsyColonFemaleHIV InfectionsHumansIntegrin alpha ChainsMaleMiddle AgedReceptors, CCR5Risk FactorsSexual Behavioralpha E integrinsAntigens, CDCCR5 protein, humanIntegrin alpha ChainsReceptors, CCR5CCR5ColonHIV transmissionmicrobiomeMSMT-cell recruitment

Identifiers

PMID32036739
PMCPMC7524317
OpenAlexW3006462474

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.