Evidence map›Paper›PMID 32036606›Full record

ReviewAdvances in experimental medicine and biology2020

Fibrocytes in the Tumor Microenvironment.

David Roife, Jason B Fleming, Richard H Gomer

Open access · greenAbstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Circulating Fibrocytes: Cellular Mediators of Tissue Fibrosis.International journal of molecular sciences · 2026
    Review
  2. Emerging Concepts in Fibroblast Biology and Progressive Pulmonary Fibrosis.Seminars in respiratory and critical care medicine · 2025
    Review
  3. Article
  4. Article
  5. Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

David RoifeDepartment of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Jason B FlemingDepartment of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Richard H GomerDepartment of Biology/ILSB, Texas A&M University, College Station, TX, USA. rgomer@tamu.edu.
Moffitt Cancer Center · USTexas A&M University · USUniversity of South Florida · US

Funding

Breaking a novel feedback loop to inhibit fibrosisR01HL132919 · NHLBI · TEXAS A&M UNIVERSITY · PI GOMER, RICHARD H · 2018 to 2021
$1.4M
NHLBI NIH HHS R01 HL132919
6 · The paper itself

Abstract

Tumors have long been compared to chronic wounds that do not heal, since they share many of the same molecular and cellular processes. In normal wounds, healing processes lead to restoration of cellular architecture, while in malignant tumors, these healing processes become dysregulated and contribute to growth and invasion of neoplastic cells into the surrounding tissues. Fibrocytes are fibroblast-like cells that differentiate from bone marrow-derived CD14

Indexed as

Tumor MicroenvironmentFibroblastsHumansNeoplasmsWound HealingBenignCancerFibroblastFibrocyteFibrosisMalignantMetastasisMicroenvironmentMonocyteMyofibroblastScarStromaTumorWound

Identifiers

PMID32036606
PMCPMC7212529
OpenAlexW3005038406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.