Evidence map›Paper›PMID 32036544›Full record

ArticleBehavior genetics2020

Adolescent Externalizing Psychopathology and Its Prospective Relationship to Marijuana Use Development from Age 14 to 30: Replication Across Independent Longitudinal Twin Samples.

Stephanie M Zellers, Robin Corley, Eric Thibodeau, Robert Kirkpatrick, Irene Elkins, William G Iacono, Christian Hopfer, John K Hewitt, Matt McGue, Scott Vrieze

Open access · greenAbstract readTwin Study
In one paragraph

Article in Behavior genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Stephanie M ZellersDepartment of Psychology, University of Minnesota, Twin Cities, N218 Elliott Hall, 75 East River Parkway, Minneapolis, MN, 55455, USA. zelle063@umn.edu.ORCID 0000-0001-8927-3483
Robin CorleyInstitute for Behavioral Genetics, and Department of Psychology & Neuroscience, University of Colorado Boulder, Boulder, USA.
Eric ThibodeauDepartment of Psychology, University of Minnesota, Twin Cities, N218 Elliott Hall, 75 East River Parkway, Minneapolis, MN, 55455, USA.
Robert KirkpatrickVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA.
Irene ElkinsDepartment of Psychology, University of Minnesota, Twin Cities, N218 Elliott Hall, 75 East River Parkway, Minneapolis, MN, 55455, USA.
William G IaconoDepartment of Psychology, University of Minnesota, Twin Cities, N218 Elliott Hall, 75 East River Parkway, Minneapolis, MN, 55455, USA.
Christian HopferDepartment of Psychiatry, University of Colorado School of Medicine, Aurora, USA.
John K HewittInstitute for Behavioral Genetics, and Department of Psychology & Neuroscience, University of Colorado Boulder, Boulder, USA.
Matt McGueDepartment of Psychology, University of Minnesota, Twin Cities, N218 Elliott Hall, 75 East River Parkway, Minneapolis, MN, 55455, USA.
Scott VriezeDepartment of Psychology, University of Minnesota, Twin Cities, N218 Elliott Hall, 75 East River Parkway, Minneapolis, MN, 55455, USA.
University of Minnesota · USUniversity of Colorado Boulder · USUniversity of Colorado Denver · USVirginia Commonwealth University · US

Funding

Twin StudyP60DA011015 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HEWITT, JOHN K. · 1997 to 2013
$22.5M
The Effects of Cannabis Legalization and Persistent Use: A Longitudinal Study of Two Twin CohortsR01DA042755 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Jarrod Martin Ellingson, SOO H RHEE · 2017 to 2026
$9.9M
TWIN STUDY OF FEMALE ALCOHOLISMS AND OTHER DISORDERSR01AA009367 · NIAAA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MCGUE, MATTHEW K. · 1992 to 2013
$9.0M
GENETICS OF ADOLESCENT ANTISOCIAL DRUG DEPENDENCER01DA012845 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HEWITT, JOHN K. · 2000 to 2012
$7.1M
Twin Family Study of Vulnerability to Substance AbuseR37DA005147 · NIDA · UNIVERSITY OF MINNESOTA · PI IACONO, WILLIAM G. · 2009 to 2018
$6.4M
A Longitudinal Study of Adopted Youth and Their FamiliesR01MH066140 · NIMH · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MCGUE, MATTHEW K. · 2003 to 2013
$5.8M
TWIN/FAMILY STUDY OF VULNERABILITY TO SUBSTANCE ABUSER01DA005147 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI IACONO, WILLIAM G · 1987 to 2007
$5.5M
Adolescent drinking and midlife outcomes: A prospective cotwin control studyR37AA009367 · NIAAA · UNIVERSITY OF MINNESOTA · PI MCGUE, MATTHEW K. · 2016 to 2024
$5.4M
TWIN STUDY OF ADHD, CD, AND SUBSTANCE ABUSER01DA013240 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI IACONO, WILLIAM G. · 2000 to 2010
$5.0M
Genetics and Progression of Early-onset Substance Dependence and HIV RiskR01DA035804 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J, STALLINGS, MICHAEL CRAIG · 2014 to 2018
$4.9M
Adult consequences of youth substance use: Twin study enriched for SUD riskR01DA036216 · NIDA · UNIVERSITY OF MINNESOTA · PI IACONO, WILLIAM G. · 2013 to 2017
$3.2M
A Twin Study of Adolescent Alcohol and Drug Use Development: Leveraging Intensive Longitudinal AssessmentsU01DA046413 · NIDA · UNIVERSITY OF MINNESOTA · PI FRIEDMAN, NAOMI P., VRIEZE, SCOTT IAN · 2018 to 2022
$2.7M
NIAAA NIH HHS R01 AA009367NIAAA NIH HHS R01 AA023974NIAAA NIH HHS R37 AA009367NIDA NIH HHS K24 DA032555NIDA NIH HHS P60 DA011015NIDA NIH HHS R01 DA005147NIDA NIH HHS R01 DA012845NIDA NIH HHS R01 DA013240NIDA NIH HHS R01 DA035804NIDA NIH HHS R01 DA036216NIDA NIH HHS R01 DA037904NIDA NIH HHS R01 DA038065NIDA NIH HHS R01 DA042755NIDA NIH HHS R37 DA005147NIDA NIH HHS U01 DA046413NIMH NIH HHS R01 MH066140
6 · The paper itself

Abstract

Externalizing psychopathology in early adolescence is a highly heritable risk factor for drug use, yet how it relates to marijuana use development is not well-characterized. We evaluate this issue in independent twin samples from Colorado (N = 2608) and Minnesota (N = 3630), assessed from adolescence to early adulthood. We used a biometric latent growth model of marijuana use frequency with data from up to five waves of assessment from ages 14 to 30, to examine change in marijuana use and its relationship with a factor model of adolescent externalizing psychopathology. The factor structure of adolescent externalizing psychopathology was similar across samples, as was the association between that common factor and early marijuana use (Minnesota r = 0.67 [0.60, 0.75]; Colorado r = 0.69 [0.59, 0.78]), and increase in use (Minnesota r = 0.18 [0.10, 0.26]; Colorado r = 0.20 [0.07, 0.34]). Early use was moderately heritable in both samples (Minnesota h

Indexed as

AdolescentAdolescent BehaviorAdultCohort StudiesColoradoFemaleGene-Environment InteractionHumansLongitudinal StudiesMaleMarijuana UseMental DisordersMinnesotaTwinsYoung AdultExternalizing psychopathologyHeritabilityLatent growth modelMarijuanaMeasurement invariance

Identifiers

PMID32036544
PMCPMC7202952
OpenAlexW3004676747

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.