ArticleEnvironmental science and pollution research international2020
Exposure to copper altered the intestinal microbiota in Chinese brown frog (Rana chensinensis).
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Caenorhabditis elegans as an experimental model for resilience-boosting microbiota interventions in nonmodel ectotherms.FEMS microbiology reviews · 2026Review
- The exploitation of nutrient metals by bacteria for survival and infection in the gut.PLoS pathogens · 2025Review
- Combined effect of seasons and life history in an anuran strengthens the response and relationship between their physiology and gut microbiota.Scientific reports · 2024Article
- Adverse Outcome Pathways for Chronic Copper Toxicity to Fish and Amphibians.Environmental toxicology and chemistry · 2022Review
- Effects of atrazine short-term exposure on jumping ability and intestinal microbiota diversity in male Pelophylax nigromaculatus adults.Environmental science and pollution research international · 2021Article
- Copper-induced sublethal effects in Bufo gargarizans tadpoles: growth, intestinal histology and microbial alternations.Ecotoxicology (London, England) · 2021Article
- Regulatory effects of transition metals supplementation/deficiency on the gut microbiota.Applied microbiology and biotechnology · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The intestinal microbiota is a crucial physiological system that offers multiple services to the host and contributes to the health of host. However, substantially less is known concerning the interrelation between amphibian gut microbiota and Cu exposure. R. chensinensis larvae were exposed to different concentrations of Cu (0, 0.1, 0.25, 0.75 μM) until reached Gosner stage 38. Histological and morphological data were measured by four Cu exposure conditions. Then, the diversity, structure, and composition of intestinal microbiota were analyzed via 16S rRNA gene sequencing. These results indicated that total body length, intestinal wet weight, and total body wet weight were reduced in 0.75 μM CuSO
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Registered trials
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