Evidence map›Paper›PMID 32035481›Full record

SynthesisBMC pediatrics2020

Standardised neonatal parenteral nutrition formulations - Australasian neonatal parenteral nutrition consensus update 2017.

Srinivas Bolisetty, David Osborn, Tim Schindler, John Sinn, Girish Deshpande, Chee Sing Wong, Susan E Jacobs, Nilkant Phad, Pramod Pharande, Rodney Tobiansky and 22 more

Open access · goldAbstract readSystematic ReviewConsensus Statement
In one paragraph

Synthesis in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Analysis of factors driving variations in neonatal parenteral nutrition over a decade: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
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  9. Review
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  11. [Expert consensus on parenteral nutrition management in neonates (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
  12. Article
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  14. Standard formulas and individualised parenteral nutrition preparations in very low birth weight infants.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 20 institutions in 4 countries.

Srinivas BolisettyRoyal Hospital for Women, Locked Bag 2000, Randwick NSW, Sydney, 2031, Australia. Srinivas.bolisetty@health.nsw.gov.au.ORCID 0000-0002-3683-6569
David OsbornRoyal Prince Alfred Hospital, Sydney, Australia.
Tim SchindlerRoyal Hospital for Women, University of New South Wales, Sydney, Australia.
John SinnUniversity of Sydney, Sydney, Australia.
Girish DeshpandeNepean Hospital, Sydney, Australia.
Chee Sing WongHospital Kuala Lumpur, Kuala Lumpur, Malaysia.
Susan E JacobsDeputy Clinical Director and Neonatal Paediatrician, The Royal Women's Hospital, Parkville, Victoria, Australia.
Nilkant PhadJohn Hunter Children's Hospital, Newcastle, Australia.
Pramod PharandeMonash Children's Hospital, Clayton, Victoria, Australia.
Rodney TobianskyLiverpool Hospital, Sydney, Australia.
Melissa LuigWestmead Hospital, Sydney, Australia.
Amit TrivediThe Children's Hospital at Westmead, Sydney, Australia.
Joanne McintoshJohn Hunter Children's Hospital, Newcastle, Australia.
Eszter JoszaRoyal Hospital for Women, Locked Bag 2000, Randwick NSW, Sydney, 2031, Australia.
Gillian OpieHead and Neonatal Paediatrician, Mercy Hospital for Women, Heidelberg, Victoria, Australia.
Lyn DowneNepean Hospital, Sydney, Australia.
Chad AndersenHead of Neonatology, Women's and Children's Hospital, North Adelaide, Australia.
Vineesh BhatiaHead of Neonatology, Women's and Children's Hospital, North Adelaide, Australia.
Prasanna KumarTownsville Hospital, Townsville, Australia.
Katri MalinenPGCert Clinical Education, PGDip Child Health (associate), Advanced Pharmacist, Townsville Hospital, Townsville, Australia.
Pita BirchGold Coast University Hospital, Southport, Australia.
Karen SimmerKing Edward Memorial Hospital for Women, Subiaco, Australia.
Gemma McLeodKing Edward Memorial and Princess Margaret Hospitals, Subiaco, Australia.
Suzanne QuaderThe Sydney Children's Hospital Network, Sydney, Australia.
Victor Samuel RajaduraiDepartment of Neonatology, KK Women's and Children's Hospital, Kampong Java, Singapore.
Michael Patrick HewsonWellington Hospital, Wellington South, New Zealand.
Arun NairWaikato Hospital, Hamilton, New Zealand.
Megan WilliamsMonash Children's Hospital, Clayton, Victoria, Australia.
Jing XiaoNepean Hospital, Penrith, Australia.
Hari RavindranathanPaediatric Intensivist, Sydney Children's Hospital, Sydney, Australia.
Roland BroadbentDunedin School of Medicine, Dunedin, New Zealand.
Kei LuiUniversity of New South Wales, Sydney, Australia.
Nepean Hospital · AUJohn Hunter Children's Hospital · AUKing Edward Memorial Hospital · AUMonash Children’s Hospital · AURoyal Hospital for Women · AUThe University of Sydney · AUTownsville Hospital · AUWomen's and Children's Hospital · AUChildren's Hospital at Westmead · AUDunedin Public Hospital · NZGold Coast Hospital · AUHospital Kuala Lumpur · MYKK Women's and Children's Hospital · SGLiverpool Hospital · AUMercy Hospital for Women · AUNew South Wales Department of Health · AURoyal Women's Hospital · AUSydney Children's Hospital · AUSydney Children’s Hospitals Network · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe first consensus standardised neonatal parenteral nutrition formulations were implemented in many neonatal units in Australia in 2012. The current update involving 49 units from Australia, New Zealand, Singapore, Malaysia and India was conducted between September 2015 and December 2017 with the aim to review and update the 2012 formulations and guidelines.

methodsA systematic review of available evidence for each parenteral nutrient was undertaken and new standardised formulations and guidelines were developed.

resultsFive existing preterm Amino acid-Dextrose formulations have been modified and two new concentrated Amino acid-Dextrose formulations added to optimise amino acid and nutrient intake according to gestation. Organic phosphate has replaced inorganic phosphate allowing for an increase in calcium and phosphate content, and acetate reduced. Lipid emulsions are unchanged, with both SMOFlipid (Fresenius Kabi, Australia) and ClinOleic (Baxter Healthcare, Australia) preparations included. The physicochemical compatibility and stability of all formulations have been tested and confirmed. Guidelines to standardise the parenteral nutrition clinical practice across facilities have also been developed.

conclusionsThe 2017 PN formulations and guidelines developed by the 2017 Neonatal Parenteral Nutrition Consensus Group offer concise and practical instructions to clinicians on how to implement current and up-to-date evidence based PN to the NICU population.

Indexed as

Parenteral NutritionParenteral Nutrition SolutionsAustraliaFish OilsHumansIndiaInfant, NewbornMalaysiaNew ZealandOlive OilSingaporeSoybean OilTriglyceridesFish OilsOlive OilParenteral Nutrition SolutionsSMOFlipidSoybean OilTriglyceridesConsensusNeonateParenteral nutritionPretermStandardisation

Identifiers

PMID32035481
PMCPMC7007668
OpenAlexW3007729261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.