Evidence map›Paper›PMID 32035310›Full record

ArticleInternational journal of surgery case reports2020

Synchronous primary neuroendocrine and mucinous epithelial tumors present in the same appendix. Case report of 2 patients.

Paul H Sugarbaker, Almog Ben-Yaacov, David Hazzan, Aviram Nissan

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Paul H SugarbakerProgram in Peritoneal Surface Malignancies, MedStar Washington Hospital Center, Washington, DC, USA. Electronic address: Paul.Sugarbaker@medstar.net.
Almog Ben-YaacovDepartment of General and Oncological Surgery - Surgery C, The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
David HazzanDepartment of General and Oncological Surgery - Surgery C, The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Aviram NissanDepartment of General and Oncological Surgery - Surgery C, The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Sheba Medical Center · ILWashington Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough uncommon, neoplasms of the appendix do exist. The two most common types are neuroendocrine tumors and mucinous appendiceal neoplasms.

methodsIn two patients unusual gross and microscopic findings in an appendectomy specimen were recorded. Special immunocytochemistry studies were used to determine the histologic type of the tumors in the appendix.

resultsThe clinical features and histopathology of two patients who had both a neuroendocrine tumor and a low grade appendiceal mucinous neoplasm in the same appendectomy specimen were described. Possibilities for the causation and treatment of this unusual condition were discussed. The incidence of this double malignancy was estimated at 2.5 in 1000 appendectomy specimens.

conclusionAlthough extremely unusual, a neuroendocrine tumor and a mucinous appendiceal neoplasm can exist in the same appendix. This condition is reported in two young patients.

Indexed as

AdenocarcinoidAppendiceal mucinous neoplasmCarcinogensCarcinoidCase seriesCytoreductive surgeryHIPECNeuroendocrine tumor

Identifiers

PMID32035310
PMCPMC7010995
OpenAlexW3002598623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.