Evidence map›Paper›PMID 32035297›Full record

ReviewClinical psychology review2020

Beyond linear mediation: Toward a dynamic network approach to study treatment processes.

Stefan G Hofmann, Joshua E Curtiss, Steven C Hayes

Open access · greenAbstract readReview
In one paragraph

Review in Clinical psychology review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 3 pooled it
22.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 223 citations in OpenAlex.

  1. Pooled it
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  11. Article
  12. Article
  13. Psychotherapy for older adults with depression: a narrative review.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  14. Article
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  20. Choice Matters: The Moderating Effect of Choice on the Relationship Between Mental Health Personal Recovery and Symptomatology.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stefan G HofmannBoston University, United States. Electronic address: shofmann@bu.edu.
Joshua E CurtissBoston University, United States.
Steven C HayesUniversity of Nevada, Reno, United States.
University of Nevada, Reno · US

Funding

Connectomes Related to Anxiety and Depression in AdolescentsU01MH108168 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GABRIELI, JOHN, WHITFIELD-GABRIELI, SUSAN · 2015 to 2019
$4.6M
Toward Outcome Measurement of Anxiety in Youth with Autism Spectrum DisordersR01MH099021 · NIMH · YALE UNIVERSITY · PI SCAHILL, LAWRENCE D. · 2012 to 2015
$2.7M
1/2-Yoga For Generalized Anxiety DisorderR01AT007257 · NCCIH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI HOFMANN, STEFAN G. · 2013 to 2017
$2.0M
Mindfulness and Acceptance Applied in Colleges Through Web-Based Guided Self-HelpR44AT006952 · NCCIH · CONTEXTUAL CHANGE, LLC · PI LEVIN, CRISSA, LEVIN, MICHAEL · 2014 to 2016
$1.1M
2/3-Dose Timing of D-cycloserine to Augment CBT for Social Anxiety DisorderR34MH099311 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI HOFMANN, STEFAN G. · 2014 to 2016
$737k
NCCIH NIH HHS R01 AT007257NCCIH NIH HHS R44 AT006952NIMH NIH HHS R01 MH099021NIMH NIH HHS R34 MH099311NIMH NIH HHS U01 MH108168
6 · The paper itself

Abstract

Few clinical scientists would disagree that more research is needed on the underlying mechanisms and processes of change in psychological therapies. In the dominant current approach, processes of change are studied through mediation. The study of mediation has been largely structured around a distinction between moderation and mediation first popularized by Baron and Kenny's (1986) seminal article, which is based on a nomothetic and cross-sectional framework. In this article, we argue that this approach is unable to adequately address change processes in psychological therapies, because it falsely assumes that treatment change is a linear, unidirectional, pauci-variate process and that the statistical assumptions are met to study processes of change in an individual using a nomothetic approach. In contrast, we propose that treatment is a dynamic process involving numerous variables that may form bi-directional and complex relationships that differ between individuals. Such relationships can best be studied using an individual dynamic network approach connected to nomothetic generalization methods that are based on a firm idiographic foundation. We argue that our proposal is available, viable, and can readily be integrated into existing research strategies. We further argue that adopting an individual dynamic network approach combined with experimental analyses will accelerate the study of treatment change processes, which is necessary as the field of evidence-based care moves toward a process-based model. We encourage future research to gather empirical evidence to examine this approach.

Indexed as

HumansPsychotherapyComplex NetworkDynamic SystemMediationProcessTherapyTreatment

Identifiers

PMID32035297
PMCPMC7137783
OpenAlexW3000381339

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.