Evidence map›Paper›PMID 32035127›Full record

ArticleProgress in cardiovascular diseases

Identification of novel genetic variants associated with cardiorespiratory fitness.

Anja Bye, Marie Klevjer, Einar Ryeng, Gustavo Jose Justo da Silva, Jose Bianco Nascimento Moreira, Dorthe Stensvold, Ulrik Wisløff

Open access · hybridAbstract readValidation Study
PubMed Publisher
In one paragraph

Article in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  8. Review
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  11. The genetics of human performance.Nature reviews. Genetics · 2022
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Anja ByeCardiac Exercise Research Group (CERG) at Dept. of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Cardiology, St. Olavs Hospital, Trondheim, Norway. Electronic address: Anja.Bye@ntnu.no.
Marie KlevjerCardiac Exercise Research Group (CERG) at Dept. of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Cardiology, St. Olavs Hospital, Trondheim, Norway.
Einar RyengGenomics Core Facility (GCF), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Gustavo Jose Justo da SilvaInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Jose Bianco Nascimento MoreiraCardiac Exercise Research Group (CERG) at Dept. of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Cardiology, St. Olavs Hospital, Trondheim, Norway.
Dorthe StensvoldCardiac Exercise Research Group (CERG) at Dept. of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Ulrik WisløffCardiac Exercise Research Group (CERG) at Dept. of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; School of Human Movement & Nutrition Sciences, University of Queensland, Brisbane, Australia.
Norwegian University of Science and Technology · NOSt Olav's University Hospital · NOInstitutt for Eksperimentell Medisinsk Forskning · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLow maximal oxygen uptake (VO

methodsWe performed a genetic association study on 123.545 single-nucleotide polymorphisms (SNPs) and directly measured VO

resultsIn the exploration cohort, 41 SNPs were associated with VO

conclusionWe discovered and validated new SNPs associated with VO

Indexed as

Cardiorespiratory FitnessModels, GeneticPolymorphism, Single NucleotideAdultAgedAged, 80 and overAnimalsCardiovascular DiseasesDatabases, GeneticExercise ToleranceFemaleGenetic Association StudiesGenetic Predisposition to DiseaseHumansMaleMiceCardiovascular disease riskGeneticsMaximal oxygen uptake

Identifiers

PMID32035127
OpenAlexW3004441378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.