ArticleThe Annals of thoracic surgery2020
HeartWare Ventricular Assist Device Cannula Position and Hemocompatibility-Related Adverse Events.
Article in The Annals of thoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- The impact of position changes of the inflow cannula in LVAD patients.Turk gogus kalp damar cerrahisi dergisi · 2026Article
- Influence of Preoperative Anatomical Characteristics on the Direction of Inflow Cannula in HeartMate 3.Artificial organs · 2025Article
- Optimization of flow rate and orientation of outflow graft at implantation for patients with left ventricular assist device.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Impact of pump position on postoperative outcomes in less invasive left ventricular assist device implantation.Frontiers in cardiovascular medicine · 2025Article
- Left ventricular assist device and pump thrombosis: the importance of the inflow cannula position.The international journal of cardiovascular imaging · 2022Article
- Inflow cannula position as risk factor for stroke in patients with HeartMate 3 left ventricular assist devices.Artificial organs · 2022Article
- Pump position and thrombosis in ventricular assist devices: Correlation of radiographs and CT data.The International journal of artificial organs · 2021Article
- Implication of Hemodynamic Assessment during Durable Left Ventricular Assist Device Support.Medicina (Kaunas, Lithuania) · 2020Review
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Authors and funding
18 authors.
Funding
Abstract
backgroundHeartWare ventricular assist device (HVAD) cannula position is associated with hemodynamics and heart failure readmissions. However, its impact on hemocompatibility-related adverse events (HRAEs) remains uncertain.
methodsHVAD patients were followed for 1 year after index hospitalization, when cannula coronal angle was quantified from chest x-ray film. Invasive right heart catheterization and transthoracic echocardiography were performed. One-year occurrences of each HRAE were compared between those with and without a cannula coronal angle of greater than 65 degrees.
resultsAmong 63 HVAD patients (median age 60 years, 63% male), 10 (16%) had a cannula coronal angle greater than 65 degrees. The wide-angle group had elevated intracardiac pressures and lower pulmonary artery pulsatility index (P < .05). They also had reduced right ventricular function by echocardiography. Freedom from HRAEs tended to be lower in the wide-angle group (24% vs 62%; P = .11). The rate of gastrointestinal bleeding was significantly higher in the greater than 65 degrees group (0.90 events/year vs 0.40 events/year; P = .013). The rates of stroke and pump thrombosis were statistically comparable irrespective of cannula angle (P > .05).
conclusionsHVAD cannula coronal angle was associated with reduced right ventricular function and HRAEs. Prospective studies evaluating surgical techniques to ensure optimal device positioning and its effects on HRAEs are warranted.
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