Evidence map›Paper›PMID 32034945›Full record

ArticleMedical physics2020

Bone material analogues for PET/MRI phantoms.

Dharshan Chandramohan, Peng Cao, Misung Han, Hongyu An, John J Sunderland, Paul E Kinahan, Richard Laforest, Thomas A Hope, Peder E Z Larson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review of imaging test phantoms.Journal of biomedical optics · 2023
    Review
  3. Synthetic PET via Domain Translation of 3-D MRI.IEEE transactions on radiation and plasma medical sciences · 2023
    Article
  4. Review
  5. Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Dharshan ChandramohanDepartment of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, 94143, USA.
Peng CaoDepartment of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, 94143, USA.
Misung HanDepartment of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, 94143, USA.
Hongyu AnDepartment of Radiology, Washington University, St. Louis, MO, 63110, USA.
John J SunderlandDepartments of Radiology, Radiation Oncology, and Physics and Astronomy, University of Iowa, Iowa City, IA, 52242, USA.
Paul E KinahanDepartment of Radiology, University of Washington, Seattle, WA, 98195, USA.
Richard LaforestDepartment of Radiology, Washington University, St. Louis, MO, 63110, USA.
Thomas A HopeDepartment of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, 94143, USA.
Peder E Z LarsonDepartment of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, 94143, USA.
University of California, San Francisco · USWashington University in St. Louis · USUniversity of Iowa · USUniversity of Washington · US

Funding

Qualification and Harmonization of PET/MRI for Cancer Clinical TrialsR01CA212148 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOPE, THOMAS, LAFOREST, RICHARD ANDRE · 2017 to 2022
$2.7M
NCI NIH HHS R01 CA212148
6 · The paper itself

Abstract

purposeTo develop bone material analogues that can be used in construction of phantoms for simultaneous PET/MRI systems.

methodsPlaster was used as the basis for the bone material analogues tested in this study. It was mixed with varying concentrations of an iodinated CT contrast, a gadolinium-based MR contrast agent, and copper sulfate to modulate the attenuation properties and MRI properties (T1 and T2*). Attenuation was measured with CT and

resultsUndoped plaster has a 511 keV attenuation coefficient (~0.14 cm

conclusionsPlaster doped with copper sulfate is a promising bone material analogue for a PET/MRI phantom, mimicking the MR properties (T1 and T2*) and 511 keV attenuation coefficient of human cortical bone.

Indexed as

Biomimetic MaterialsCortical BonePhantoms, ImagingBone and BonesMagnetic Resonance ImagingPositron-Emission Tomographyattenuation correctionbone materialsdoped plasterPET/MRI

Identifiers

PMID32034945
PMCPMC7901472
OpenAlexW2981801560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.