Evidence map›Paper›PMID 32034698›Full record

ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2020

In vitro inhibitory effect of two commercial probiotics on chromogenic actinomycetes.

E Gobbi, M A De Francesco, G Piccinelli, A Caruso, E Bardellini, A Majorana

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In one paragraph

Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

E GobbiAgrifood and Environmental Microbiology Platform (PiMiAA-AgroFood Lab), Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0001-7565-5966
M A De FrancescoDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0003-2221-6286
G PiccinelliDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0002-7346-1380
A CarusoDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0001-5178-566X
E BardelliniDepartment of Medical and Surgical Specialities, Radiological Sciences and Public Health, Dental School, Dental Clinic, University of Brescia, p.le Spedali Civili 1, 25 133, Brescia, Italy. elena.bardellini@unibs.it.ORCID http://orcid.org/0000-0002-3955-4794
A MajoranaDepartment of Medical and Surgical Specialities, Radiological Sciences and Public Health, Dental School, Dental Clinic, University of Brescia, p.le Spedali Civili 1, 25 133, Brescia, Italy.ORCID http://orcid.org/0000-0003-0252-533X
University of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBlack extrinsic discoloration is a common clinical and aesthetic problem. This study aims to evaluate the potential in vitro antagonistic activity of two commercial probiotics, Streptococcus salivarius M18 and Lactobacillus reuteri ProDentis, against microorganisms associated with black stains.

methodsStreptococcus salivarius M18 and Lactobacillus reuteri were tested against Aggregatibacter actinomycetemcomitans and Actinomyces naeslundiiusing their cell-free fermentative broth in a planktonic growth inhibition test.

resultsBoth probiotic cell-free supernatants showed the ability to reduce the pathogenic bacteria growth in a dose-dependent way. Streptococcus salivarius M18 showed a stronger antimicrobial activity than Lactobacillus reuteri ProDentis against the two indicator strains used. A. naeslundi was less susceptible to the probiotic activity of both S. salivarius and L. reuteri compared to A. actinomycetemcomitans.

conclusionsThe obtained results demonstrate a potent antagonistic ability of probiotics to reduce the growth of microorganisms associated with black tooth stains. Therefore, these strains could be evaluated for a therapeutic use against dental pigmentations.

Indexed as

ActinobacteriaLimosilactobacillus reuteriProbioticsActinomycesAggregatibacter actinomycetemcomitansHumansActinomyces naeslundiiAggregatibacter actinomycetemcomitansBlack stainLactobacillus reuteriStreptococcus salivarius M18

Identifiers

PMID32034698
OpenAlexW3004807441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.