ArticleClinical oral investigations2020
Relationship between vertical facial pattern and brain structure and shape.
Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Evaluation of Morphology and Location of Greater Palatine Foramen (GPF) in Different Sagittal Facial Types: A CBCT Study in an Iranian Adult Population.International journal of dentistry · 2025Article
- The influence of facial types on the morphology and location of the greater palatine foramen: a CBCT study.Oral radiology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesDolichofacial (long-faced) and brachyfacial (short-faced) individuals show specific and well-differentiated craniofacial morphology. Here, we hypothesise that differences in the basicranial orientation and topology between dolicho- and brachyfacial subjects could be associated with differences in the supporting brain tissues. MATERIAL AND
methodsBrain volumes (total intracranial, grey matter, and white matter volume), cortical thickness, and the volumes and shapes of fifteen subcortical nuclei were assessed on the basis of magnetic resonance imaging in 185 subjects. Global, voxel-wise and shape analyses, as well as multiple regression models, were generated to evaluate the association between vertical facial variations (dolicho- and brachyfacial spectrum) and brain morphology.
resultsSeveral differences in brain anatomy between dolicho- and brachyfacial subjects, along with relevant associations between vertical facial indices and brain structure and shape, were found. The most relevant finding of this study is related to the strong association of vertical facial indices with the volumes and shapes of subcortical nuclei, as the dolichofacial pattern increased, the bilateral hippocampus and brain stem expanded, while the left caudate, right pallidus, right amygdala, and right accumbens decreased in volume.
conclusionsLong- and short-faced human subjects present differences in brain structure and shape. CLINICAL SIGNIFICANT: The results of our study increase the clinician's knowledge about brain structure in dolicho- and brachyfacial patients. The findings could be of interest since the affected brain areas are involved in higher cognitive functions in humans, including language, memory, and attention.
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