ArticleClinical research in cardiology : official journal of the German Cardiac Society2020
Temporal trends in incidence and outcome of acute coronary syndrome.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05619601 (Gender Differences in Prevention Strategies and Therapeutic Adherence After Acute Myocardial Infarction - GENAMI PREVENTION), which is not on this map. Cited by 48 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Gender Differences in Prevention Strategies and Therapeutic Adherence After Acute Myocardial Infarction - GENAMI PREVENTION
Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Global Insights into Chronic Obstructive Pulmonary Disease and Coronary Artery Disease: A Systematic Review and Meta-Analysis of 6,400,000 Patients.Reviews in cardiovascular medicine · 2024Pooled it
- Predictors of Mortality in Patients Treated with Veno-Arterial ECMO for Cardiogenic Shock Complicating Acute Myocardial Infarction: a Systematic Review and Meta-Analysis.Journal of cardiovascular translational research · 2022Pooled it
- A systematic review and meta-analysis of percutaneous coronary intervention compared to coronary artery bypass grafting in non-ST-elevation acute coronary syndrome.Scientific reports · 2022Pooled it
- Hypothermia in patients with acute myocardial infarction: a meta-analysis of randomized trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Pooled it
- Colchicine effectively attenuates inflammatory biomarker high-sensitivity C-reactive protein (hs-CRP) in patients with non-ST-segment elevation myocardial infarction: a randomised, double-blind, placebo-controlled clinical trial.Inflammopharmacology · 2021Trial
- GLP-1 receptor agonists in atherosclerotic cardiovascular disease and diabetes mellitus or obesity: investigation of the potential role in a German inpatient dataset.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Prognostic Significance of Malnutrition Indices in ST-Elevation Myocardial Infarction: A Comparative Analysis of CONUT and PNI Scores After Primary PCI.Diagnostics (Basel, Switzerland) · 2026Article
- Predicting Contrast-Induced Nephropathy in NSTEMI: The Role of the HALP Score.Medicina (Kaunas, Lithuania) · 2025Article
- Preoperative dual antiplatelet therapy increases risk after urgent coronary bypass surgery: A Netherlands heart registration study.JTCVS open · 2025Article
- The Impact of Combining CIRS-G and Clinical Frailty Score on One-Month Mortality in Acute Coronary Syndrome.Healthcare (Basel, Switzerland) · 2025Article
- Article
- Risk factors of acute coronary syndrome among patients admitted to cardiac care units at governmental hospitals in the Gaza Strip: Case- control study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Variations in Prehospital Analgesic Use Based on Pain Etiology.Biomedicines · 2025Article
- Article
- Temporal trends in mortality due to coronary heart disease in Germany from 1998 to 2023.Journal of health monitoring · 2025Article
- Article
- Frailty prevalence, invasive treatment frequency, and in-hospital outcome in patients hospitalized for acute coronary syndrome in Germany (2005-2022): a nationwide registry study.The Lancet regional health. Europe · 2025Article
- Characteristics and risk factors for mortality in patients with acute coronary syndrome concomitant sepsis: a retrospective multicenter cohort study.Frontiers in cardiovascular medicine · 2025Article
- Nonlinear relationship between blood urea nitrogen to albumin ratio and in-hospital mortality in non-diabetic patients with non-ST-segment elevation myocardial infarction.Frontiers in nutrition · 2025Article
- Divergent trends in the incidence and mortality of acute myocardial ischaemic syndrome, especially in women. Evidence from Finland in 1996-2021.Annals of medicine · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to investigate changes of incidence, outcome and related interventions of patients with acute coronary syndrome (ACS) over the past decade in Germany.
methodsData on the international statistical classification of diseases and procedural codes from the Federal Bureau of Statistics in Germany was used. This included all ACS cases in Germany in the years 2005-2015. Analyses were performed separately for the diagnoses of overall ACS, ST-elevation myocardial infarction (MI), non-ST-elevation MI and unstable angina pectoris. Procedures including coronary angiography and percutaneous coronary intervention and the endpoint in-hospital mortality were assessed.
resultsBetween 2005 and 2015 a total of 3797,546 cases of ACS were recorded. The mean age was 69 years and 36% were females. In-hospital mortality was 6.3%, 62% underwent coronary angiography and 42% received percutaneous coronary intervention. In-hospital mortality was highest for patients with ST-elevation MI (12.0%) and lowest for patients with unstable angina pectoris (0.6%). From 2005 to 2015 the incidence rates of ACS, ST-elevation MI and unstable angina pectoris decreased, while the incidence rate of non-ST-elevation MI increased. The percentages of performed coronary angiographies and percutaneous coronary interventions increased from 52 to 70% and 34 to 50%, respectively. The adjusted incidence rate of in-hospital mortality decreased from 64.9 cases per 1000 person-years to 54.8 cases.
conclusionIn a large dataset including more than 3.7 million cases, we report an increase in coronary procedures and a reduction of ACS incidence and related mortality in the past decade in Germany.
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