Evidence map›Paper›PMID 32034446›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Prediction of survival in patients with IDH-wildtype astrocytic gliomas using dynamic O-(2-[

Elena K Bauer, Gabriele Stoffels, Tobias Blau, Guido Reifenberger, Jörg Felsberg, Jan M Werner, Philipp Lohmann, Jurij Rosen, Garry Ceccon, Caroline Tscherpel and 8 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Review
  3. Assessment of the Type and Degree of Genomic Instability in Gliomas.International journal of molecular sciences · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Contribution of [Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  8. DeepDixon synthetic CT for [Frontiers in neuroscience · 2023
    Article
  9. Combination of pre-treatment dynamic [European journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Article
  11. Article
  12. Impact ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Dynamic amino-acid PET in neuro-oncology: a prognostic tool becomes essential.European journal of nuclear medicine and molecular imaging · 2021
    Article
  17. Article
  18. DynamicCancers · 2021
    Article
  19. Cancers · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Elena K BauerDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937, Cologne, Germany.
Gabriele StoffelsInstitute of Neuroscience and Medicine (INM-3, -4, -5), Research Centre Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Tobias BlauDepartment of Neuropathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Guido ReifenbergerInstitute of Neuropathology, Heinrich Heine University, Duesseldorf, Germany.
Jörg FelsbergInstitute of Neuropathology, Heinrich Heine University, Duesseldorf, Germany.
Jan M WernerDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937, Cologne, Germany.
Philipp LohmannInstitute of Neuroscience and Medicine (INM-3, -4, -5), Research Centre Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Jurij RosenDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937, Cologne, Germany.
Garry CecconDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937, Cologne, Germany.
Caroline TscherpelDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937, Cologne, Germany.
Marion RappCenter of Integrated Oncology (CIO), University of Duesseldorf, Duesseldorf, Germany.
Michael SabelCenter of Integrated Oncology (CIO), University of Duesseldorf, Duesseldorf, Germany.
Christian P FilssInstitute of Neuroscience and Medicine (INM-3, -4, -5), Research Centre Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Nadim J ShahInstitute of Neuroscience and Medicine (INM-3, -4, -5), Research Centre Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Bernd NeumaierInstitute of Neuroscience and Medicine (INM-3, -4, -5), Research Centre Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Gereon R FinkDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937, Cologne, Germany.
Karl-Josef LangenInstitute of Neuroscience and Medicine (INM-3, -4, -5), Research Centre Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Norbert GalldiksDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener St. 62, 50937, Cologne, Germany. n.galldiks@fz-juelich.de.ORCID 0000-0002-2485-1796
Forschungszentrum Jülich · DEUniversity of Cologne · DEHeinrich Heine University Düsseldorf · DE

Funding

Wilhelm Sander-Stiftung 2016/069/1
6 · The paper itself

Abstract

purposeIntegrated histomolecular diagnostics of gliomas according to the World Health Organization (WHO) classification of 2016 has refined diagnostic accuracy and prediction of prognosis. This study aimed at exploring the prognostic value of dynamic O-(2-[

methodsBefore initiation of treatment, dynamic FET PET imaging was performed in patients with newly diagnosed glioblastoma (GBM) and anaplastic astrocytoma (AA). Static FET PET parameters such as maximum and mean tumour/brain ratios (TBR

resultsSixty patients (45 GBM and 15 AA patients) of two university centres were retrospectively identified. Patients with isocitrate dehydrogenase (IDH)-mutant or O

conclusionsOur data suggest that dynamic FET PET allows the identification of patients with longer OS among patients with newly diagnosed IDH-wildtype GBM and AA.

Indexed as

AstrocytomaBrain NeoplasmsHumansIsocitrate DehydrogenaseNeoplasm GradingPositron-Emission TomographyRetrospective StudiesTyrosineIsocitrate DehydrogenaseTyrosineFET PETHigh-grade gliomaIDH mutationMGMT promoter methylationOverall survival

Identifiers

PMID32034446
PMCPMC7188701
OpenAlexW3004860779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.