Evidence map›Paper›PMID 32034252›Full record

ArticleScientific reports2020

Application and Evaluation of Highly Automated Software for Comprehensive Stent Analysis in Intravascular Optical Coherence Tomography.

Hong Lu, Juhwan Lee, Martin Jakl, Zhao Wang, Pavel Cervinka, Hiram G Bezerra, David L Wilson

Erratum issuedOpen access · goldAbstract readEvaluation Study
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Harnessing Artificial Intelligence for Innovation in Interventional Cardiovascular Care.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
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  19. Article
  20. [Structural design and biomechanical numerical analysis of body-fitted stent in stenotic vessels].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Hong LuMicrosoft, Azure Global, Cambridge, MA, 02142, USA.
Juhwan LeeDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA.
Martin JaklUniversity of Defense, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic.
Zhao WangDepartment of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Pavel CervinkaDepartment of Cardiology, Krajska zdravotni a.s., Masaryk Hospital, UJEP Usti nad Labem, Usti nad Labem, Czech Republic.
Hiram G BezerraCardiovascular Imaging Core Laboratory, Harrington Heart & Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
David L WilsonDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA. dlw@case.edu.
Case Western Reserve University · USKrajská Zdravotní · CZMassachusetts Institute of Technology · USMicrosoft Research (United Kingdom) · GBUniversity of Defence · CZ

Funding

Computer assisted coronary artery stent interventionsR01HL143484 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BEZERRA, HIRAM, WILSON, DAVID LYNN · 2018 to 2021
$2.9M
In vivo Characterization of Stents using Intravascular OCT ImagingR01HL114406 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BEZERRA, HIRAM, ROLLINS, ANDREW MARTIN · 2013 to 2016
$1.7M
Coronary Plaque Characterization with Vascular OCT ImagingR21HL108263 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI COSTA, MARCO A, WILSON, DAVID LYNN · 2011 to 2012
$423k
BIOMEDICAL ENGINEERING RESEARCH FACILITIESC06RR012463 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI KUTINA, KENNETH L · 1997 to 1997
–
NCRR NIH HHS C06 RR012463NHLBI NIH HHS R01 HL114406NHLBI NIH HHS R01 HL143484NHLBI NIH HHS R21 HL108263
6 · The paper itself

Abstract

Intravascular optical coherence tomography (IVOCT) is used to assess stent tissue coverage and malapposition in stent evaluation trials. We developed the OCT Image Visualization and Analysis Toolkit for Stent (OCTivat-Stent), for highly automated analysis of IVOCT pullbacks. Algorithms automatically detected the guidewire, lumen boundary, and stent struts; determined the presence of tissue coverage for each strut; and estimated the stent contour for comparison of stent and lumen area. Strut-level tissue thickness, tissue coverage area, and malapposition area were automatically quantified. The software was used to analyze 292 stent pullbacks. The concordance-correlation-coefficients of automatically measured stent and lumen areas and independent manual measurements were 0.97 and 0.99, respectively. Eleven percent of struts were missed by the software and some artifacts were miscalled as struts giving 1% false-positive strut detection. Eighty-two percent of uncovered struts and 99% of covered struts were labeled correctly, as compared to manual analysis. Using the highly automated software, analysis was harmonized, leading to a reduction of inter-observer variability by 30%. With software assistance, analysis time for a full stent analysis was reduced to less than 30 minutes. Application of this software to stent evaluation trials should enable faster, more reliable analysis with improved statistical power for comparing designs.

Indexed as

Endovascular ProceduresHumansSensitivity and SpecificitySoftwareStentsTomography, Optical Coherence

Identifiers

PMID32034252
PMCPMC7005885
OpenAlexW3005455668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.