ArticleScientific reports2020
Microtubules as Sub-Cellular Memristors.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Self-referential processing as the biological switch between classical and quantum functioning of the brain.Frontiers in human neuroscience · 2026Article
- High-frequency signals: a comparison between the cable equation and telegrapher's equations in nerves.BMC biomedical engineering · 2025Article
- TUBA1B as a novel prognostic biomarker correlated with immunosuppressive tumor microenvironment and immunotherapy response.Frontiers in pharmacology · 2025Article
- Consciousness and spintronic coherence in microtubules.Communicative & integrative biology · 2025Article
- Shape, membrane morphology, and morphodynamic response of metabolically active human mitochondria revealed by scanning ion conductance microscopy.Beilstein journal of nanotechnology · 2025Article
- Scan-Rate-Dependent Ion Current Rectification in Bipolar Interfacial Nanopores.Micromachines · 2024Article
- A novel conductive microtubule hydrogel for electrical stimulation of chronic wounds based on biological electrical wires.Journal of nanobiotechnology · 2024Article
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- Selectively advantageous instability in biotic and pre-biotic systems and implications for evolution and aging.Frontiers in aging · 2024Review
- Emerging cancer therapies: targeting physiological networks and cellular bioelectrical differences with non-thermal systemic electromagnetic fields in the human body - a comprehensive review.Frontiers in network physiology · 2024Review
- Extended Higher-Order Elements with Frequency-Doubled Parameters: The Hysteresis Loops Are Always of Type II.Sensors (Basel, Switzerland) · 2023Article
- The electrical properties of isolated microtubules.Scientific reports · 2023Article
- There's Plenty of Room Right Here: Biological Systems as Evolved, Overloaded, Multi-Scale Machines.Biomimetics (Basel, Switzerland) · 2023Article
- Toward a holographic brain paradigm: a lipid-centric model of brain functioning.Frontiers in neuroscience · 2023Article
- Extended and Generic Higher-Order Elements for MEMS Modeling.Sensors (Basel, Switzerland) · 2022Article
- Electrical Propagation of Condensed and Diffuse Ions Along Actin Filaments.Journal of computational neuroscience · 2022Article
- Computational Investigation of the Ordered Water System Around Microtubules: Implications for Protein Interactions.Frontiers in molecular biosciences · 2022Article
- Virus-Induced Membrane Fusion in Neurodegenerative Disorders.Frontiers in cellular and infection microbiology · 2022Review
- Low-energy amplitude-modulated radiofrequency electromagnetic fields as a systemic treatment for cancer: Review and proposed mechanisms of action.Frontiers in medical technology · 2022Review
- Generation of Electromagnetic Field by Microtubules.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Memristors represent the fourth electrical circuit element complementing resistors, capacitors and inductors. Hallmarks of memristive behavior include pinched and frequency-dependent I-V hysteresis loops and most importantly a functional dependence of the magnetic flux passing through an ideal memristor on its electrical charge. Microtubules (MTs), cylindrical protein polymers composed of tubulin dimers are key components of the cytoskeleton. They have been shown to increase solution's ionic conductance and re-orient in the presence of electric fields. It has been hypothesized that MTs also possess intrinsic capacitive and inductive properties, leading to transistor-like behavior. Here, we show a theoretical basis and experimental support for the assertion that MTs under specific circumstances behave consistently with the definition of a memristor. Their biophysical properties lead to pinched hysteretic current-voltage dependence as well a classic dependence of magnetic flux on electric charge. Based on the information about the structure of MTs we provide an estimate of their memristance. We discuss its significance for biology, especially neuroscience, and potential for nanotechnology applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.