Evidence map›Paper›PMID 32034075›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2020

Noriko Sato, Kate Stringaris, Jan K Davidson-Moncada, Robert Reger, Stephen S Adler, Cynthia Dunbar, Peter L Choyke, Richard W Childs

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. First-in-human dosimetry and biodistribution of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Homotypic Targeting of [Pharmaceutics · 2025
    Article
  9. Article
  10. Article
  11. In vivo tracking of ex-vivo-generatedMolecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  12. Article
  13. In Vivo PET Imaging ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Evaluation of differentScientific reports · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Noriko SatoMolecular Imaging Program, NCI, NIH, Bethesda, Maryland. saton@mail.nih.gov.ORCID 0000-0002-9372-1725
Kate StringarisCellular and Molecular Therapeutics Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Jan K Davidson-MoncadaCellular and Molecular Therapeutics Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Robert RegerCellular and Molecular Therapeutics Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Stephen S AdlerClinical Research Directorate, Frederick National Laboratory for Cancer Research sponsored by the NCI, Frederick, Maryland.ORCID 0000-0002-4399-6923
Cynthia DunbarTranslational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.ORCID 0000-0002-7645-838X
Peter L Choyke *Molecular Imaging Program, NCI, NIH, Bethesda, Maryland.
Richard W Childs *Cellular and Molecular Therapeutics Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
National Heart Lung and Blood Institute · USNational Institutes of Health · USFrederick National Laboratory for Cancer Research · US

Funding

Allogeneic Immunotherapy for cancer and nonmalignant hematological disordersZIAHL002345 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHILDS, RICHARD · 2009 to 2025
$53.3M
Understanding hematopoietic stem cell mobilization and engraftmentZIAHL006063 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DUNBAR, CYNTHIA E · 2010 to 2025
$23.5M
Intracellular In vivo ImagingZIABC010657 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHOYKE, PETER L · 2009 to 2025
$20.3M
A Phase II Study Evaluating Fostamatinib for Hospitalized Adults with COVID-19.ZIAHL006250 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHILDS, RICHARD · 2020 to 2023
$2.4M
CCR NIH HHS HHSN261200800001CIntramural NIH HHS ZIA BC010657Intramural NIH HHS ZIA HL002345NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

purposeTrials of adoptive natural killer (NK)-cell immunotherapy for hematologic malignancies have thus far shown only marginal effects, despite the potent EXPERIMENTAL

designRM NK cells were expanded

resultsNK cells retained sufficient levels of

conclusionsThese data support translation of this technique to humans to track the distribution of adoptively infused cells and to develop novel techniques to improve immune cell homing to tumor microenvironments.

Indexed as

AnimalsCell TrackingCell TransplantationKiller Cells, NaturalLungMacaca mulattaMonitoring, PhysiologicOxyquinolinePositron-Emission TomographyRadioisotopesTissue DistributionZirconiumOxyquinolineRadioisotopesZirconiumZirconium-89

Identifiers

PMID32034075
PMCPMC7269806
OpenAlexW3004433211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.