Trial reportClinical journal of the American Society of Nephrology : CJASN2020
Screening for CKD To Improve Processes of Care among Nondiabetic Veterans with Hypertension: A Pragmatic Cluster-Randomized Trial.
Trial report in Clinical journal of the American Society of Nephrology : CJASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Pooled it
- Pooled it
- The Effectiveness of Pharmacist Interventions in the Management of Patient with Renal Failure: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Pragmatic Trial of Hospitalization Rate in Chronic Kidney Disease.The New England journal of medicine · 2024Trial
- Kidney disease screening at ART initiation among adults with HIV in Uganda: A missed priority for a high-risk population.PLOS global public health · 2026Article
- Implementation of a Kidney Screening Intervention to Improve Early CKD Detection in Adults with Diabetes.Kidney360 · 2025Article
- Risk Factor-Based Screening for Early Detection of Chronic Kidney Disease in Primary Care Settings: A Systematic Review.Kidney medicine · 2025Article
- Pharmacists delivering hypertension care services: a systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2025Article
- Early Detection of Chronic Kidney Disease in Mexico, a Case for Policy Transfer.Risk management and healthcare policy · 2025Article
- Trends in using of antihypertensive medication among US CKD adults, NHANES 2001-2018.Frontiers in cardiovascular medicine · 2023Article
- Patient Care Gaps Prior to Maintenance Dialysis Initiation: A Population-Based Retrospective Study.Canadian journal of kidney health and disease · 2023Article
- Improving chronic kidney disease detection and treatment in the United States: the chronic kidney disease cascade of care (CBMC nephrology · 2022Article
- Moving Beyond Tools and Building Bridges: Lessons Learned From a CKD Decision Support in Primary Care.Kidney medicine · 2022Article
- Digital Health Interventions to Enhance Prevention in Primary Care: Scoping Review.JMIR medical informatics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesWe conducted a pilot, pragmatic, cluster-randomized trial to evaluate feasibility and preliminary effectiveness of screening for CKD using a triple-marker approach (creatinine, cystatin C, and albumin/creatinine ratio), followed by education and guidance, to improve care of hypertensive veterans in primary care. We used the electronic health record for identification, enrollment, intervention delivery, and outcome ascertainment. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We randomized 1819 veterans without diabetes but with hypertension (41 clusters) into three arms: (
resultsMedian age was 68 years, 55% were white, 1658 (91%) had a prior creatinine measure, but only 172 (9%) had prior urine albumin/creatinine ratio, and 83 (5%) had a prior cystatin C measure. Among those in the intervention, 527 of 1215 (43%) were identified with upcoming appointments to have CKD screening. Of these, 367 (69%) completed testing. Among those tested, 77 (21%) persons had newly diagnosed CKD. After 1 year, change in systolic BP was -1 mm Hg (interquartile range, -11 to 11) in usual care, -2 mm Hg (-11 to 11) in the screen-educate arm, and -2 mm Hg (-13 to 10) in the screen-educate plus pharmacist arm;
conclusionsThe pragmatic design made identification, enrollment, and intervention delivery highly efficient. The limited ability to identify appointments resulted in inadequate between-arm differences in CKD testing rates to determine whether screening improves clinical outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.