Evidence map›Paper›PMID 32034042›Full record

ReviewThe Journal of experimental biology2020

Evolution, developmental expression and function of odorant receptors in insects.

Hua Yan, Shadi Jafari, Gregory Pask, Xiaofan Zhou, Danny Reinberg, Claude Desplan

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of experimental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 144 citations in OpenAlex.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Hua YanDepartment of Biology, University of Florida, Gainesville, FL 32611, USA.
Shadi JafariDepartment of Molecular Biology, Umeå University, 901 87 Umeå, Sweden.
Gregory PaskDepartment of Biology, Bucknell University, Lewisburg, PA 17837, USA.
Xiaofan ZhouGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, 510642 Guangzhou, China.
Danny ReinbergHoward Hughes Medical Institute (HHMI), Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
Claude DesplanDepartment of Biology, New York University, New York, NY 10003, USA cd38@nyu.edu.ORCID 0000-0002-6914-1413
New York University · USBucknell University · USHoward Hughes Medical Institute · USSouth China Agricultural University · CNUniversity of Florida · US

Funding

Stochastic choices in the retina and optic lobesR01EY013010 · NEI · NEW YORK UNIVERSITY · PI DESPLAN, CLAUDE · 1999 to 2025
$9.1M
Aging and rejuvenation: An ant model to study the regulation of longevityR01AG058762 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Claude Desplan, DANNY REINBERG · 2018 to 2026
$6.2M
Howard Hughes Medical InstituteNEI NIH HHS R01 EY013010NIA NIH HHS R01 AG058762
6 · The paper itself

Abstract

Animals rely on their chemosensory system to discriminate among a very large number of attractive or repulsive chemical cues in the environment, which is essential to respond with proper action. The olfactory sensory systems in insects share significant similarities with those of vertebrates, although they also exhibit dramatic differences, such as the molecular nature of the odorant receptors (ORs): insect ORs function as heteromeric ion channels with a common Orco subunit, unlike the G-protein-coupled olfactory receptors found in vertebrates. Remarkable progress has recently been made in understanding the evolution, development and function of insect odorant receptor neurons (ORNs). These studies have uncovered the diversity of olfactory sensory systems among insect species, including in eusocial insects that rely extensively on olfactory sensing of pheromones for social communication. However, further studies, notably functional analyses, are needed to improve our understanding of the origins of the Orco-OR system, the mechanisms of ORN fate determination, and the extraordinary diversity of behavioral responses to chemical cues.

Indexed as

Receptors, OdorantAnimalsInsectaInsect ProteinsPheromonesSmellInsect ProteinsPheromonesReceptors, OdorantAntDevelopmentDiversityDrosophilaEvolutionOdorant ReceptorOlfactionOrco

Identifiers

PMID32034042
PMCPMC7790194
OpenAlexW3004715820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.